How much pomegranate juice per day is too much?

No nutrient here reaches an NIH upper limit, the FDA caffeine figure or a Dietary Guidelines limit within 60 of these servings a day. One cup (8 fl oz) = 1 cup, 8 fl oz (249 g). USDA FoodData Central, Pomegranate juice, bottled. Limits count everything you eat and drink that day, so other foods and supplements use up part of each one.

• Level B In a 4-week trial of 51 healthy adults aged 30 to 50, 11 fl oz (330 mL) of pomegranate juice a day lowered systolic pressure by 3.1 mm Hg and diastolic by 2.3 mm Hg. Plant Foods Hum Nutr, 2012
• Level B In 21 adults with high blood pressure, 5.1 fl oz (150 mL) of fresh pomegranate juice a day for 2 weeks lowered systolic and diastolic pressure compared with water. Phytotherapy Research, 2014 (blood pressure and endothelial effects of pomegranate juice in hypertensive subjects)
• Level B In 60 people with type 2 diabetes, 6.8 fl oz (200 mL) of pomegranate juice a day for 6 weeks left systolic and diastolic pressure lower than in a no-juice group. Clin Nutr ESPEN, 2019
• Level B In women with polycystic ovary syndrome, 10 fl oz (300 mL) a day of pomegranate juice for 8 weeks left blood pressure lower than a placebo drink. J Endocrinol Invest, 2020
• Level B In a crossover RCT of 53 men with mild to moderate erectile dysfunction, 8 fl oz (237 mL) of pomegranate juice daily for 4 weeks did not significantly beat placebo on erection scores. Forest et al., International Journal of Impotence Research, 2007

Only studies that give the amount eaten. Levels: A is a meta-analysis of trials, B a randomized trial, C an observational study. How we grade evidence.

• Level D A woman on steady warfarin who drank pomegranate juice 2 to 3 times a week had her INR fall below target after she stopped the juice. Pharmacotherapy, 2009
• Level E According to NCCIH, pomegranate juice is believed to be safe, though digestive symptoms and allergic reactions have been reported. NIH National Center for Complementary and Integrative Health, Pomegranate: Usefulness and Safety, updated April 2025
• Level D A UK emergency case report links pomegranate juice to unstable warfarin anticoagulation and advises asking patients with unstable INR about juice intake. Emerg Med J, 2010

If you have kidney disease, take blood thinners or other medicines, or are pregnant, the right amount for you is a question for your clinician.

No agency limits pomegranate juice, and nothing in it reaches an upper limit. Calories are the practical ceiling: two cups are 269 calories.

In 51 healthy adults, 11 fl oz (330 mL) a day for 4 weeks lowered systolic pressure by 3.1 mm Hg compared with a control drink (Level B). The meta-analysis put the systolic drop at about 6 mm Hg for up to 10 fl oz (300 mL) a day (Level A).

If you take warfarin, two case reports link pomegranate juice to unstable INR (Level D), although a study in volunteers found no change in the enzyme pathway that clears warfarin (Level B). The UK case report advises clinicians to ask about juice when INR is unstable, so tell yours if you drink it.

Evidence behind this note

1. Level B In a 4-week trial of 51 healthy adults aged 30 to 50, 11 fl oz (330 mL) of pomegranate juice a day lowered systolic pressure by 3.1 mm Hg and diastolic by 2.3 mm Hg. Plant Foods Hum Nutr, 2012
2. Level A In the 14-trial meta-analysis, up to 10 fl oz (300 mL) of pomegranate juice a day cut systolic pressure by about 6 mm Hg, while more than 10 fl oz (300 mL) a day did not clearly lower it. Phytotherapy Research, 2023 (impact of pomegranate juice on blood pressure: systematic review and meta-analysis)
3. Level D A UK emergency case report links pomegranate juice to unstable warfarin anticoagulation and advises asking patients with unstable INR about juice intake. Emerg Med J, 2010
4. Level D A woman on steady warfarin who drank pomegranate juice 2 to 3 times a week had her INR fall below target after she stopped the juice. Pharmacotherapy, 2009
5. Level B In human volunteers, pomegranate juice did not change clearance of a CYP2C9 probe drug, the enzyme pathway that clears warfarin, although it blocked the enzyme in the test tube. Clin Pharmacol Ther, 2012

Written from the data and studies on this page, reviewed by the Bioma editorial system. How we verify.

• Pomegranate juice: what the research says