Ginger: what the supplement trials found

Almost everything known about ginger and health was measured in capsules, powders and extracts. The trials behind this page gave people supplements, often 1 to 2 g of dried ginger a day, and none of the studies cited here tested fresh root as eaten in food. Read every number below as a number about a supplement. The best result is modest. Across 12 randomized trials, ginger supplements lowered blood pressure by about 5 mmHg systolic and 2 mmHg diastolic, and the reviewers rated that evidence low in certainty. For nausea in pregnancy, 13 trials with 1,174 women found ginger eased the nausea compared with placebo. It did not significantly cut vomiting and did no better than vitamin B6. As a weight-loss aid it fails: the largest review, 36 trials, found no change in body weight or BMI. One warning is concrete. Among 171 people on warfarin, those using ginger had about three times the odds of reporting bleeding in a diary. The EU medicines agency gives at most 2.5 g of powdered root a day for motion sickness and 3 g a day for other uses, the closest thing to an upper dose from any agency.

Every statement here is tied to a source. The badge says what kind of evidence stands behind it: A is a meta-analysis or systematic review, E is the position of an expert body without its own analysis. How we verify →

The numbers, per 3.5 oz (100 g)

USDA entry	kcal	Protein	Fat	Carbs	Fiber
Ginger, ground	335	8.98 g	4.24 g	71.6 g	14.1 g

These are the USDA entries that are ginger, not foods made from it; they differ in cut, part, pack or preparation. Linked names have a page with the full profile and per-portion figures.

What your body absorbs

After 2 g of ginger extract by mouth, free 6-gingerol, the main pungent compound, was not detectable in blood at any time over 24 hours. It circulated as glucuronide and sulfate conjugates that peaked at 1 hour and had half-lives of 1 to 3 hours, with no build-up on daily dosing. — human volunteers given 2.0 g ginger extract by mouth Evidence C source
Free 6- and 8-gingerol not detected in plasma 0.25 to 24 h. Glucuronides peaked at 1 h (6-gingerol 0.47 ug/mL). Half-lives 1 to 3 h, no accumulation
In 19 healthy adults given 2 g of red ginger in water, 10-gingerol and 6-shogaol reached peak blood levels within 30 to 40 minutes and had elimination half-lives of about 5.6 and 2.5 hours. — healthy subjects in Indonesia, single dose of red ginger suspension (2 g/15 ml) (n = 19) Evidence C source
Cmax 10-gingerol 160.49 ng/ml at 38 min, 6-shogaol 453.40 ng/ml at 30 min. Elimination half-lives 336 and 149 min

What cooking and storage change

Lab studies reviewed in 2022 show that heating, drying or long storage turns gingerols into shogaols, so dried ginger had over 9 times more 6-shogaol than fresh ginger in both yellow and white varieties. — ginger rhizome, fresh versus dried or steamed, food-chemistry studies (n = 42 articles) Evidence D source
Gingerols dehydrate to shogaols with heating, drying or long storage. 6-shogaol over 9 times higher in dried than fresh ginger
Lab data cited in the same review suggest 6-gingerol is stable up to body temperature but about half breaks down above 60 C, while 6-shogaol holds up better and loses half only at 80 C. — 6-gingerol and 6-shogaol heated in a kinetic study cited by the review (n = 42 articles) Evidence D source
6-gingerol stable to 37 C, about 50% degraded above 60 C. 6-shogaol loses 50% at 80 C

What it does to your health

A 2026 meta-analysis of 12 randomized trials found ginger supplements lowered systolic blood pressure by about 5 mmHg and diastolic by about 2 mmHg, with low certainty. — adults in randomized controlled trials of ginger supplementation, searched to May 2026 Evidence A source
SBP WMD -5.03 mmHg (95% CI -8.49 to -1.57); DBP WMD -2.03 mmHg (95% CI -3.90 to -0.15); GRADE low (inconsistency)
An earlier 2019 meta-analysis of 6 randomized trials with 345 people found ginger lowered systolic blood pressure by about 6 mmHg, with very high variation between trials. — adults in human clinical trials of ginger supplementation, searched to September 2018 (n = 345) Evidence A source
SBP MD -6.36 mmHg (95% CI -11.27 to -1.46; I2 89.8%); DBP MD -2.12 mmHg (95% CI -3.92 to -0.31; I2 73.4%)
A 2026 systematic review pooling 41 randomized trials on heart risk markers found ginger lowered systolic blood pressure by about 2.7 mmHg, with no effect on diastolic. — adults in 41 RCTs of ginger supplementation, searched to January 2025 Evidence A source
SBP WMD -2.72 mmHg (95% CI -5.25 to -0.19); DBP among outcomes with no significant effect
A 2020 systematic review of 109 ginger trials found 7 on stomach function, and all but one that measured gastric emptying reported ginger speeding digestion. — randomized controlled trials of ginger in humans; subset examining gastric function (emptying, dysrhythmia) (n = 109 RCTs; 7 on gastric function) Evidence A source
Gastric emptying faster with ginger in all trials measuring it except one (paracetamol absorption method); no pooled estimate
In a randomized double-blind crossover trial of 24 healthy adults, 1.2 g of ginger halved gastric half-emptying time to 13.1 minutes from 26.7 on placebo, without changing gut symptoms. — healthy volunteers after an 8 h fast; 1200 mg ginger capsules or placebo, then 17 fl oz (500 ml) low-nutrient soup (n = 24) Evidence B source
Gastric half-emptying time 13.1 vs 26.7 min (P < 0.01); more antral contractions; no difference in GI symptoms
In a pilot crossover trial of 11 healthy volunteers, one capsule of a ginger and artichoke extract before a meal left a 24% smaller stomach area an hour later than placebo. — healthy volunteers; one capsule of standardized ginger plus artichoke extract (Prodigest) or placebo before a standardized meal (n = 11) Evidence B source
Post-meal gastric area 8.4 vs 11.0 cm2, -24% vs placebo, p < 0.001
In the same 2026 review, adding ginger to a preventive drug lowered headache pain by about 3 points at 3 months in 2 trials with 183 people, with low certainty. — people with migraine taking a preventive drug, with ginger added versus the drug with or without placebo (n = 183) Evidence A source
Headache pain severity at 3 months pooled MD -3.18 (95% CI -3.94 to -2.42); 2 studies; low certainty
For an acute attack, the 2026 review rated ginger added to ketoprofen as making little or no difference to pain at 2 hours, based on 1 trial of 60 people. — adults treated for a migraine attack with intravenous ketoprofen plus ginger or placebo (n = 60) Evidence A source
Headache severity at 2 hours MD 1.27 lower (95% CI 1.46 lower to 1.08 lower); low certainty
A 2021 meta-analysis of 3 placebo-controlled trials found ginger raised the chance of being pain-free at 2 hours by 79%, from a small evidence base. — migraine patients in 3 RCTs of ginger versus placebo, searched to September 2020 (n = 3 RCTs) Evidence A source
Pain-free at 2 h RR 1.79 (95% CI 1.04 to 3.09); pain score at 2 h MD -1.27 (95% CI -1.46 to -1.07)
In an emergency-room RCT of 60 adults, 400 mg of ginger extract added to ketoprofen gave a better response at 1 to 2 hours than ketoprofen with placebo. — adults with episodic migraine seen in the emergency room during an attack; 400 mg ginger extract (5% active ingredient) or placebo plus 100 mg intravenous ketoprofen (n = 60) Evidence B source
Better clinical response at 1 h (p = 0.04), 1.5 h (p = 0.01) and 2 h (p = 0.04)
In a 3-month RCT of 107 people with episodic migraine, 200 mg of ginger extract three times a day prevented attacks no better than placebo. — adults 18 to 60 with episodic migraine, not on preventive medication; 200 mg dry ginger extract (5% active ingredient) three times daily or placebo for 3 months (n = 107) Evidence B source
Proportion with at least 50% fewer attacks did not differ between ginger and placebo
In an RCT of 100 people with migraine without aura, ginger powder eased attacks about as well as sumatriptan at 2 hours. — patients with acute migraine without aura, randomized to ginger powder or sumatriptan, five attacks each (n = 100) Evidence B source
Mean headache severity fell at 2 hours in both groups; efficacy similar
In a pilot RCT of 60 people, a sublingual feverfew and ginger product left 32% pain-free at 2 hours versus 16% on placebo. — adults meeting IHS migraine criteria with 2 to 6 attacks a month, treating attacks early at the mild headache stage; 45 active, 15 placebo (n = 60) Evidence B source
Pain-free at 2 h 32% vs 16% (P = .02); pain relief 63% vs 39% (P = .002)
In a 2026 RCT of 60 people with migraine, 8 weeks of a curcumin, gingerol and piperine supplement lowered headache severity but not attack frequency or duration. — patients with migraine; two capsules daily, each with 300 mg curcumin, 7.5 mg gingerol and 3.75 mg piperine, or placebo, for 8 weeks (n = 60) Evidence B source
Headache severity change -1.93 vs -0.36 (VAS, P = 0.001); frequency P = 0.737 and duration P = 0.873, no difference
A 2025 dose-response meta-analysis of 29 RCTs found ginger supplements lowered CRP by 0.86 mg/L, TNF-alpha by 1.90 pg/mL and IL-6 by 1.15 pg/mL. — adults in 29 randomized controlled trials of ginger supplementation (n = 29 trials) Evidence A source
CRP WMD -0.86 mg/L (95% CI -1.10 to -0.62); TNF-alpha WMD -1.90 pg/mL (-2.61 to -1.18); IL-6 WMD -1.15 pg/mL (-1.90 to -0.41)
Pooling 16 RCTs with 1010 people, ginger lowered CRP, hs-CRP and TNF-alpha, with heterogeneity above 89% for each. — participants of 16 randomized controlled trials of ginger supplementation (n = 1010) Evidence A source
CRP SMD -5.11 (95% CI -7.91 to -2.30, I2 98.1%); hs-CRP SMD -0.88 (-1.63 to -0.12); TNF-alpha SMD -0.85 (-1.48 to -0.21)
A meta-analysis of 9 studies found ginger lowered CRP by 0.84 mg/L, and the size of the drop did not depend on the dose. — participants of 9 prospective studies of ginger supplementation (n = 9 studies) Evidence B source
CRP WMD -0.84 mg/L (95% CI -1.38 to -0.31, I2 56.3%); meta-regression on dose slope -0.20 (95% CI -0.95 to 0.55), p=0.60
In an RCT of 30 adults with joint pain, 125 mg a day of a ginger extract for 58 days eased pain and shifted several inflammatory markers. — 30 men and women aged about 56 with mild to moderate joint and muscle pain, 125 mg/d ginger extract (10% gingerols) or placebo for 58 days (n = 30) Evidence B source
Lower muscle pain ratings, better stiffness and function; changes in IL-6, IFN-gamma, TNF-alpha and CRP mainly after 2 days of recovery from exercise
A 2024 meta-analysis of 27 RCTs with 1309 adults found ginger lowered body weight by about 3.3 lb (1.5 kg), with low certainty of evidence. — adults in RCTs of ginger supplementation, searched to August 2022 (n = 1309) Evidence A source
Body weight WMD -3.4 lb (95% CI -5.2 to -1.5; metric: -1.52 kg, -2.37 to -0.66); BMI WMD -0.58 kg/m2 (-0.87 to -0.30); GRADE low for weight, very low for BMI and waist
A 2022 meta-analysis of 26 trials found that the change in body weight, -0.52, was not statistically significant in the few trials that measured it. — participants in randomized controlled trials of ginger, searched to December 2021 (n = 26 trials) Evidence A source
BMI -0.49 (95% CI -0.79 to -0.18); body weight -0.52 (-1.48 to 0.43), not significant; doses above 1500 mg/day for over 8 weeks did better for weight
In a 12-week double-blind RCT of 80 overweight Korean adults, 480 mg a day of steamed ginger extract cut weight by 2.2 lb (1.0 kg) while the placebo group showed a non-significant gain of 1.4 lb (0.63 kg). — adults aged 18 to 60 years with BMI 25.0 to 29.9 kg/m2 (n = 80) Evidence B source
Body weight -1.00 +/- 1.88 kg vs +0.63 +/- 1.92 kg on placebo (between groups p = 0.001); body fat -1.18 points vs +0.37
A meta-analysis of 12 RCTs found ginger lowered pregnancy nausea scores by 1.2 points on a 10-point scale more than placebo, in the two trials that could be pooled. — pregnant women with nausea and vomiting of pregnancy; two placebo-controlled trials pooled for change in VAS nausea score, 4 days of treatment (n = 2 trials) Evidence A source
VAS nausea MD 1.20 (95% CI 0.56 to 1.84), I2 0%; no difference between >=1500 mg and <1500 mg a day
A meta-analysis of 13 RCTs with 1,174 women found ginger improved overall pregnancy nausea symptoms and nausea severity versus placebo, but not vomiting. — pregnant women in randomized trials of ginger vs placebo or vitamin B6 (n = 1,174) Evidence A source
General symptoms OR 7.475 (95% CI 4.133 to 13.520); nausea SMD 0.821 (0.585 to 1.056); vomiting SMD 0.549 (-0.268 to 1.365)
A 2026 network meta-analysis of 24 placebo-controlled RCTs with 3,017 women found ginger might reduce pregnancy nausea, with low to moderate certainty. — pregnant women with nausea and vomiting of pregnancy in placebo-controlled RCTs (n = 3,017) Evidence A source
Ginger among interventions that might be effective; quince, B6 combinations, P6 acupressure and dimenhydrinate ranked highest; CINeMA low to moderate
In an Australian equivalence RCT of 291 women under 16 weeks pregnant, 1.05 g of ginger a day for 3 weeks was compared with 75 mg of vitamin B6. — 291 women less than 16 weeks pregnant, teaching hospital in Australia (n = 291) Evidence B source
Nausea MD 0.2 (90% CI -0.3 to 0.8); retching 0.3 (-0.0 to 0.6); vomiting 0.5 (0.0 to 0.9)
In a triple-blind RCT of 77 women at 6 to 16 weeks, 500 mg of ginger twice a day for 4 days beat placebo and did not differ significantly from vitamin B6 on the total Rhodes score. — pregnant women with mild to moderate nausea and vomiting at 6-16 weeks; 28 ginger, 26 B6, 23 placebo (n = 77) Evidence B source
Ginger vs placebo p = .039; ginger vs B6 total Rhodes score p = .128
Across 12 randomized trials, ginger supplements lowered systolic blood pressure by about 5 mmHg and diastolic by about 2 mmHg, with low certainty of evidence. — Adults in 12 randomized trials; larger effects at 2,000 mg/day or more and with raised baseline blood pressure (n = 12 trials) Evidence A source
SBP -5.03 mmHg (95% CI -8.49 to -1.57); DBP -2.03 mmHg (95% CI -3.90 to -0.15)
A meta-analysis of 29 trials found ginger supplements lowered C-reactive protein by 0.86 mg/L, with high heterogeneity between studies. — Adults in 29 randomized trials, many with underlying conditions (n = 29 trials) Evidence A source
CRP -0.86 mg/L (95% CI -1.10 to -0.62)
A steamed ginger extract at 480 mg a day for 12 weeks reduced body fat percentage and fat mass versus placebo in 80 overweight adults, a result that applies to this processed extract rather than to fresh ginger. — 80 overweight adults aged 18-60, BMI 25.0-29.9, 12 weeks (n = 80) Evidence B source
Lower body fat percentage and fat mass by DEXA vs placebo; sizes not given in abstract
A single 1 g dose of dried ginger powder raised fat oxidation by 13.5% two hours later when taken in the morning, but not in the afternoon, and did not change body temperature. — Healthy young men, single dose at 82 °F (28 degrees C) ambient temperature Evidence B source
Fat oxidation +13.5% at 120 min (morning only)

Safety, limits and interactions

In a clinical study of healthy and hypertensive adults, ginger strengthened the anti-clotting effect of the blood pressure drug nifedipine on platelets. — normal human volunteers and hypertensive patients; 1 g ginger with 10 mg nifedipine per day Evidence C source
Ginger potentiated nifedipine's inhibition of platelet aggregation (synergistic); size not given in abstract
Among 171 warfarin users who kept a 16-week diary, ginger was one of the products linked with more self-reported bleeding. — 171 adults on warfarin anticoagulation, Canadian hospital, 16-week diary (n = 171) Evidence C source
Ginger use associated with increased risk of self-reported bleeding
A 2021 systematic review of 149 reports lists ginger among foods and herbs that raise bleeding risk in people taking warfarin. — reports of food, herbal or supplement interactions with warfarin, 5 databases to December 2019 Evidence C source
Ginger named among products with increased bleeding risk on warfarin
Across 109 ginger trials, side effects were mostly mild gut complaints, with heartburn reported in 16 studies. — randomized controlled trials of ginger reporting adverse effects (n = 109 RCTs; 17 reported adverse effects) Evidence A source
Heartburn in 16 studies, nausea in 5, diarrhea in 2; also abdominal pain, bloating, gas, epigastric distress
The 2019 review of ginger in gut disorders found side effects rare and mild, mostly heartburn, belching and stomach discomfort. — clinical trials of ginger in gastrointestinal disorders Evidence A source
Rare, mild: heartburn, belching, bruising or flushing, rash, GI discomfort; adverse events generally not higher than control
The EU medicines agency lists stomach upset, belching, indigestion, heartburn and nausea as common side effects of ginger root, in 1 to 10 users in 100. — users of ginger root medicinal products Evidence E source
Common (>= 1/100 to < 1/10)
NCCIH notes that ginger taken by mouth can cause abdominal discomfort, heartburn and diarrhea, and advises people on any medicine to check with a clinician first. — people taking ginger supplements by mouth Evidence E source
Possible abdominal discomfort, heartburn, diarrhea, mouth and throat irritation
In the 100-person RCT comparing ginger powder with sumatriptan, ginger caused fewer side effects than the drug. — patients with acute migraine without aura, ginger powder or sumatriptan (n = 100) Evidence B source
Clinical adverse effects fewer with ginger powder than sumatriptan; size not given in abstract
In the 60-person sublingual feverfew and ginger trial over 1 month, the most common side effects were oral numbness and nausea. — adults with migraine treating attacks with sublingual feverfew and ginger or placebo (n = 60) Evidence B source
Generally well tolerated; oral numbness and nausea most frequent adverse events
Among 171 warfarin users who kept a 16-week diary, ginger was one of the products linked with more self-reported bleeding. — 171 adults on warfarin anticoagulation, Canadian hospital, 16-week diary (n = 171) Evidence C source
Ginger use associated with increased risk of self-reported bleeding
Across 39 knee osteoarthritis RCTs with 4599 patients, none of seven supplements, ginger included, raised adverse events compared with placebo. — adults with knee osteoarthritis in 39 RCTs of eggshell membrane, vitamin D, Boswellia, curcumin, ginger, krill oil or collagen (n = 4599) Evidence A source
No increase in adverse events vs placebo
In the 12-week steamed ginger extract trial, 6 of 40 people on the extract and 2 of 40 on placebo reported adverse events, with no significant difference between groups. — overweight adults aged 18 to 60 years (n = 80) Evidence B source
Adverse events 6 vs 2 participants, no significant difference; all mild; no serious events; laboratory values normal
NCCIH notes that ginger taken by mouth can cause abdominal discomfort, heartburn and diarrhea. — people taking ginger by mouth Evidence E source
Possible abdominal discomfort, heartburn, diarrhea, mouth and throat irritation
Across the trials in this meta-analysis, side effects such as heartburn, drowsiness and miscarriage were no more common with ginger than with placebo. — pregnant women in placebo-controlled ginger trials; most took about 1000 mg ginger a day for 4 days (n = 12 trials) Evidence A source
No significant difference vs placebo for allergic reaction, spontaneous abortion, abdominal discomfort, diarrhea, drowsiness, headache, heartburn
A 2026 umbrella review of 18 systematic reviews concluded that 450 to 1950 mg of ginger a day reduces pregnancy nausea more than vomiting, without more miscarriage, heartburn or drowsiness. — 18 systematic reviews (8 with meta-analysis) of ginger for nausea and vomiting of pregnancy (n = 18 reviews) Evidence A source
Benefit vs placebo on severity and occurrence; clearer for nausea than vomiting; reviews mostly low methodological quality (AMSTAR-2 mean 11.77)
Single trials collected in the 2026 network meta-analysis reported heartburn (3 to 12%), sedation (11%), loose stools (3%), dizziness (3%) and arrhythmia (1.6%) among women taking ginger. — pregnant women taking ginger supplements in included RCTs Evidence B source
Loose stools 2.94%, heartburn 12.1% and 3.2%, sedation 11.1%, arrhythmia 1.6%, dizziness 3.12%
In a Thai double-blind RCT of 138 women comparing 500 mg ginger three times a day with vitamin B6 for 3 days, minor sedation and heartburn occurred in both arms, with no significant difference. — women with nausea and vomiting of pregnancy at or before 16 weeks, Bangkok; 64 per group analyzed (n = 138) Evidence B source
Nausea score 5.0 to 3.6 with ginger; sedation 26.6% vs 32.8%, heartburn 9.4% vs 6.3% (ginger vs B6), not significant
In the Norwegian Mother and Child Cohort of 68,522 women, ginger use in pregnancy, reported by 1,020 women, was not associated with a higher risk of congenital malformations. — 68,522 pregnant women, Norwegian Mother and Child Cohort; ginger use self-reported at weeks 17 and 30 and 6 months after birth (n = 68,522) Evidence C source
No increased risk of congenital malformations, stillbirth/perinatal death, preterm birth, low birth weight or low Apgar score
Among 171 people taking warfarin followed for 16 weeks, those using ginger had about three times the odds of self-reported bleeding. — 171 adults on warfarin in a Canadian hospital, 16-week diary (n = 171) Evidence C source
Self-reported bleeding OR 3.20 (95% CI 2.42 to 4.24)
A systematic review of warfarin interactions lists ginger among foods and herbs that clinicians should watch for increased bleeding risk. — 149 reports on 78 foods, herbs and supplements with warfarin (n = 149 reports) Evidence C source
Ginger listed as raising bleeding risk; no pooled estimate
The EU medicines agency's ginger root monograph caps motion sickness use at 2.5 g of powdered root a day and gives 0.25 to 1 g three times daily for its other traditional uses, which tops out at 3 g a day. It is the closest thing to an upper dose from an agency. — adolescents, adults and elderly using ginger root medicinal products Evidence E source
Motion sickness: up to 2.5 g powdered root a day. Other traditional uses: 0.25 to 1 g three times daily (at most 3 g a day)
The EU medicines agency lists no known drug interactions and no reported overdose for ginger root, and says toxic effects in animal studies of up to 12 months appeared only above doses people normally take. — users of ginger root medicinal products Evidence E source
Interactions: none known. Overdose: no case reported. Toxic doses in repeat-dose animal studies above normal human use
In a randomized crossover trial in 12 healthy men, a week of ginger at recommended doses did not change the clotting time (INR) or blood levels after a single warfarin dose, nor platelet aggregation on its own. — healthy men given one 25 mg warfarin dose alone or after 7 days of ginger at recommended doses (n = 12) Evidence B source
INR AUC ratio 1.01 (90% CI 0.93 to 1.15) with ginger. S-warfarin clearance ratio 1.05 (0.97 to 1.13). Platelet aggregation unchanged
A 2015 systematic review of 10 studies found that 4 of 8 clinical trials reported less platelet clumping with ginger and 4 reported no effect, so whether ginger thins the blood remains unsettled. — adults in studies measuring platelet aggregation after ginger versus placebo or baseline (n = 10 studies) Evidence C source
4 of 8 clinical trials found reduced platelet aggregation, 4 found no effect. 2 observational studies mixed. Evidence equivocal
A 2008 systematic review of herb-drug interactions named ginger among the herbs most often involved, and found blood thinners such as warfarin and aspirin among the drugs most often implicated. — published reports of herb-drug interactions, Natural Standard Research Collaboration Evidence C source
Ginger among the herbs most often involved in herb-drug interactions. Anticoagulant and antiplatelet drugs (warfarin, aspirin) frequently implicated

What people believe that the data does not support

NCCIH does not list blood pressure among ginger's studied uses and advises anyone taking a medicine to talk with a clinician before using ginger. — people taking any medicine Evidence E source
Consult a clinician before using ginger with medicines
The EU medicines agency accepts ginger root for mild spasmodic gut complaints with bloating and flatulence only as a traditional remedy, based on long use. — adults Evidence E source
Traditional use indication; well-established use is limited to preventing nausea and vomiting in motion sickness
NCCIH advises anyone taking a medicine to talk with a health care provider before using ginger, because some herbs and medicines interact in harmful ways. — people taking any medicine Evidence E source
Consult a clinician before using ginger with medicines
NCCIH advises people taking any medicine to talk with a clinician before using ginger, because some herbs and medicines interact. — people taking medicines Evidence E source
Check with a health care provider before use
A 2018 network meta-analysis of 42 trials found adequate evidence for use in pregnancy nausea only for ginger, with the quality of that evidence moderate. — pregnant women in randomized trials of treatments for nausea and vomiting of pregnancy (n = 42 trials) Evidence A source
Ginger and vitamin B6 associated with better vomiting control and fewer adverse events; adequate evidence only for ginger, quality moderate
An NIHR systematic review of 73 studies found ginger better than placebo for nausea and vomiting of pregnancy, alongside antihistamines, metoclopramide and vitamin B6. — women with nausea and vomiting of pregnancy or hyperemesis gravidarum; 6 ginger vs placebo and 6 ginger vs B6 trials (n = 73 studies) Evidence A source
Ginger better than placebo; no pooled estimate (heterogeneity); findings may not transfer across severities
A systematic review of 48 pregnancy care guidelines found some consensus on recommending ginger and vitamin B6 for nausea and vomiting. — 48 clinical practice guidelines relevant to Australian pregnancy care (n = 48 guidelines) Evidence E source
No effect size; guideline consensus
A meta-analysis of 27 trials with 1,309 adults linked ginger supplements to about 3.3 lb (1.5 kg) lower body weight, but rated the certainty of that evidence as low. — 1,309 adults in 27 randomized trials; effective dose estimated at 2 g/day for more than 8 weeks (n = 1309) Evidence A source
Body weight -3.4 lb (95% CI -5.2 to -1.5; metric: -1.52 kg, -2.37 to -0.66)
A larger 2025 meta-analysis of 36 trials found ginger did not reduce body weight or BMI, and cut waist size by only 0.26 in (0.65 cm), so ginger as a weight-loss aid is not supported. — Adults in 36 randomized trials (n = 36 trials) Evidence A source
Waist -0.26 in (95% CI -0.42 to -0.09; metric: -0.65 cm, -1.07 to -0.24); no effect on body weight or BMI

Who this works differently for

In the same 2026 meta-analysis, the drop in blood pressure was seen mainly in people with raised blood pressure or obesity and at doses of 2 g a day or more. — subgroups of RCTs: elevated baseline BP, obesity, doses of 2000 mg/day or more Evidence A source
Subgroup-specific reductions; nonlinear inverse dose-response; duration had no meaningful influence
In people with type 2 diabetes, a 2026 meta-analysis of 4 trials found ginger lowered systolic blood pressure by only about 1.6 mmHg and did not change diastolic. — adults with type 2 diabetes in placebo-controlled RCTs, 1200 to 3000 mg/day for 8 to 12 weeks; BP pooled from 4 trials Evidence A source
SBP MD -1.62 mmHg (95% CI -3.01 to -0.24; I2 6.09%); DBP MD -2.41 mmHg (95% CI -5.45 to 0.64; ns)
In a 2026 crossover RCT of 35 healthy adults, 1.5 g of dried ginger a day for 6 weeks did not change blood pressure. — thirty-five healthy participants, dried ginger powder capsules 1500 mg/day or placebo, 6 weeks each, 4-week washout (n = 35) Evidence B source
No significant effect on blood pressure, lipids or body weight
A 2022 meta-analysis of diet and supplement trials in reflux found ginger-containing supplements raised the odds of symptom relief about 7.5-fold, but this rests on only 2 studies of combined products. — adults with a history of GERD or functional dyspepsia; dietary, nutraceutical and probiotic interventions (n = 21 studies in the review; 2 studies pooled for ginger-containing supplements) Evidence A source
Incidence of GERD symptom alleviation OR 7.50 (95% CI 3.62 to 15.54), GRADE high, n = 2 studies
The same 2020 review of 109 trials found the only trial in irritable bowel syndrome showed no reduction in symptoms with ginger. — randomized controlled trials of ginger; irritable bowel syndrome patients (n = 109 RCTs; 1 in IBS) Evidence A source
No evidence of symptom reduction in IBS (p > 0.05)
A 2019 systematic review of ginger trials in gut disorders concluded that ginger speeds gastric emptying in healthy people and in functional dyspepsia, without changing symptoms. — clinical trials of ginger in gastrointestinal disorders; healthy volunteers and functional dyspepsia Evidence A source
Faster gastric emptying and more antral contractions; no change in fundus dimension, GI symptoms or gut peptides
In a randomized double-blind crossover trial of 11 people with functional dyspepsia, 1.2 g of ginger sped gastric emptying but did not improve symptoms. — patients with functional dyspepsia; three capsules of ginger (1.2 g total) or placebo, then 17 fl oz (500 mL) low-nutrient soup (n = 11) Evidence B source
Median half-emptying time 12.3 (8.5-17.0) vs 16.1 (8.3-22.6) min, P <= 0.05; symptoms, GLP-1, motilin, ghrelin unchanged
In a 12-week placebo-controlled trial of 52 people with relapsing multiple sclerosis, 500 mg of ginger three times a day with meals reduced constipation, nausea and bloating severity. — patients with relapsing-remitting multiple sclerosis; 500 mg ginger or placebo (corn) 3 times a day with main meals (n = 52) Evidence B source
Bloating severity -11.57 vs +3.97 mm VAS (P = 0.047), frequency P = 0.098; constipation frequency -23.63 vs +14.81 (P < 0.001)
In a 28-day pilot trial of 45 people with irritable bowel syndrome, ginger at 1 g or 2 g a day did no better than a brown sugar placebo. — IBS patients; placebo (brown sugar), 1 g or 2 g ginger daily for 28 days (n = 45) Evidence B source
Responders 57.1% placebo, 46.7% 1 g, 33.3% 2 g (p > .05); adequate relief 53.3% in both; side effects 35.7% placebo vs 16.7% ginger
In a 12-week multicentre placebo-controlled trial of 80 adults with mild to moderate functional dyspepsia, 480 mg a day of steamed ginger extract improved gut symptom scores including indigestion and reflux. — adults with mild to moderate functional dyspepsia; steamed ginger extract GGE03 480 mg/day or placebo for 12 weeks (n = 80) Evidence B source
GSRS total and sub-scores (abdominal pain, constipation, indigestion, reflux) improved vs placebo, p < 0.001
In an uncontrolled 4-week study of 51 people with functional dyspepsia taking 1080 mg of ginger root a day, symptoms improved in 63.7%. — outpatients with functional dyspepsia, H. pylori negative; 540 mg ginger root capsule before lunch and dinner for 4 weeks (n = 51 completers of 124 assessed) Evidence C source
Improvement in 63.7%; epigastric pain -44%, nausea -43%, early satiety -30%, postprandial fullness -20%, heartburn -12% vs baseline
In an open-label 8-week study of 47 people with functional dyspepsia on 1080 mg of ginger root a day, the most common side effects were mild bloating, heartburn and diarrhea. — adults 18 to 72 with Rome IV functional dyspepsia; 2 capsules of 540 mg ginger root powder per day; anticoagulant users excluded (n = 47) Evidence C source
Bloating 14.9%, heartburn 12.8%, diarrhea 10.6%, headache 2.1%; no discontinuations, no serious events
The EU medicines agency advises avoiding ginger root medicines in pregnancy as a precaution. — pregnant and breastfeeding women; children and adolescents Evidence E source
Avoid in pregnancy (precaution)
In type 2 diabetes, 5 RCTs showed ginger lowered hs-CRP by 0.42 mg/L, but every included trial was at high risk of bias. — patients with type 2 diabetes in 5 randomized controlled trials (n = 5 trials) Evidence A source
Hs-CRP WMD -0.42 mg/L (95% CI -0.78 to -0.05); TNF-alpha -2.13 pg/mL; IL-6 -0.61 pg/mL
In knee osteoarthritis, 3 trials with 330 patients found ginger lowered pain but no other clinical measure. — patients with knee osteoarthritis, 166 on ginger and 164 on placebo in 3 studies (n = 330) Evidence A source
Pain decreased significantly; stiffness, function and quality of life not changed
A 2025 network meta-analysis of knee osteoarthritis trials found ginger cut pain on a 100-point scale by about 12 points against placebo. — adults with knee osteoarthritis in placebo-controlled RCTs, ginger arm from six studies (n = 4599 (whole network)) Evidence A source
VAS pain MD 11.89 (95% CI 1.01 to 22.49) vs placebo
Among 171 warfarin users who kept a 16-week diary, ginger was one of the products linked with more self-reported bleeding. — 171 adults on warfarin anticoagulation, Canadian hospital, 16-week diary (n = 171) Evidence C source
Ginger use associated with increased risk of self-reported bleeding
A 2019 meta-analysis of 14 RCTs with 473 overweight or obese people found ginger lowered body weight on a standardized scale (SMD -0.66), with an interval that nearly reaches no effect. — overweight and obese subjects in RCTs, searched to November 2017 (n = 473) Evidence A source
Body weight SMD -0.66 (95% CI -1.31 to -0.01); waist-to-hip ratio SMD -0.49 (-0.82 to -0.17); BMI SMD -0.65 (-1.36 to 0.06), not significant
Among 171 warfarin users who kept a 16-week diary, ginger was one of the products linked with more self-reported bleeding. — 171 adults on warfarin anticoagulation, Canadian hospital, 16-week diary (n = 171) Evidence C source
Ginger use associated with increased risk of self-reported bleeding
Most trials gave about 1000 mg of ginger powder a day, split into three or four doses, for 4 days, and lower doses under 1500 mg a day looked at least as effective. — pregnant women with nausea and vomiting of pregnancy in the included trials (n = 12 trials) Evidence A source
Typical regimen 1000 mg/day for 4 days; subgroup favored <1500 mg/day
Against vitamin B6, the same meta-analysis found no significant difference for overall symptoms, nausea or vomiting. — pregnant women in randomized trials comparing ginger with vitamin B6 (n = 1,174) Evidence A source
General symptoms OR 1.239 (95% CI 0.495 to 3.102); nausea SMD 0.199 (-0.102 to 0.500); vomiting SMD 0.331 (-0.145 to 0.808)
Among 171 people taking warfarin followed for 16 weeks, those using ginger had about three times the odds of self-reported bleeding. — 171 adults on warfarin, 16-week diary (n = 171) Evidence C source
Self-reported bleeding OR 3.20 (95% CI 2.42 to 4.24)
In people with type 2 diabetes, a meta-analysis of 13 placebo-controlled trials found ginger lowered fasting glucose by 16 mg/dl and HbA1c by 0.41 percentage points, changes the authors judged of limited clinical importance. — Adults with type 2 diabetes in 13 randomized placebo-controlled trials (n = 13 trials) Evidence A source
FBS -16.27 mg/dl (95% CI -25.75 to -6.80); HbA1c -0.41% (95% CI -0.63 to -0.20)
In a meta-analysis of 13 trials with 1,174 pregnant women, ginger eased nausea compared with placebo (SMD 0.82) but did not significantly reduce vomiting, and did no better than vitamin B6. — 1,174 pregnant women with nausea and vomiting in 13 randomized trials (n = 1174) Evidence A source
Nausea severity SMD 0.821 (95% CI 0.585 to 1.056) vs placebo; vomiting not significant; no difference vs vitamin B6
In a Danish cohort of 225 women in early pregnancy, 11.1% took ginger supplements, mostly as a general health boost rather than for nausea. — 225 pregnant women at gestational weeks 10-16, Denmark (n = 225) Evidence C source
11.1% used ginger supplements
NCCIH states that ginger supplements may be safe in pregnancy but that little is known about their safety while breastfeeding. — Pregnant and breastfeeding women Evidence E source
Position statement, no effect size

What is still unknown

In the 2019 meta-analysis, blood pressure fell only in trials of people aged 50 or younger, lasting 8 weeks or less, and using 3 g of ginger a day or more. — subgroups of 6 RCTs by mean age, dose and duration (n = 345) Evidence A source
Significant SBP and DBP falls only with mean age <= 50 y, follow-up <= 8 weeks, ginger >= 3 g/day
A 2022 meta-analysis in type 2 diabetes reported a larger 4.2 mmHg systolic drop from 5 effect sizes, but with almost total disagreement between trials. — adults with type 2 diabetes in RCTs of ginger, English-language, searched to September 2021 Evidence A source
SBP WMD -4.20 (95% CI -7.64 to -0.77; I2 97%); DBP WMD -1.61 (95% CI -3.04 to -0.18; I2 93.2%)
In an 8-week RCT of 204 people with type 2 diabetes, 3 g of ginger a day in tea did not change blood pressure differently from the other spices or plain tea. — type 2 diabetes patients given 3 g cinnamon, 3 g cardamom, 1 g saffron or 3 g ginger with three glasses of black tea, or tea alone, for 8 weeks (n = 204) Evidence B source
No significant between-group difference in BP
In a 2-week placebo-controlled trial of 51 healthy young adults, 1.2 g a day of ginger root powder shifted some gut bacteria but did not change bowel function or overall gut symptoms. — healthy adults aged 18 to 30; 1.2 g/d ginger (84 mg/d gingerols and shogaols) or microcrystalline cellulose for 14 days (n = 51) Evidence B source
No change in bowel function, gastrointestinal symptoms, alpha or beta diversity; some gut bacteria shifted
A 2026 systematic review of 8 randomized trials with 594 patients concluded it is too uncertain whether ginger works for treating or preventing migraine. — patients with migraine in randomized trials of ginger alone or as an add-on, versus placebo or active drugs; searched to April 2026 (n = 594) Evidence A source
Certainty of evidence low to very low for all outcomes; no firm conclusion on acute or preventive use
The same 29-trial meta-analysis says the benefit is mainly in people with underlying health conditions and that high heterogeneity calls for caution. — adults in 29 RCTs, healthy and with chronic disease (n = 29 trials) Evidence A source
Larger effect in unhealthy participants; IL-6 effect non-linear with dose and duration
In the same 16-trial meta-analysis, ginger did not significantly change IL-6 or the adhesion molecule sICAM. — participants of 16 randomized controlled trials of ginger supplementation (n = 1010) Evidence A source
IL-6 SMD -0.45 (95% CI -1.29 to 0.38); sICAM SMD -0.05 (-0.36 to 0.26)
A meta-analysis of 47 rheumatoid arthritis trials of dietary polyphenols found only one trial of ginger extract. — patients with rheumatoid arthritis in 47 RCTs of 15 dietary polyphenols (n = 3852) Evidence A source
Ginger extract tested in 1 RCT; polyphenols overall did not increase adverse events
A 2025 meta-analysis of 36 RCTs concluded that ginger does not seem to improve body weight or BMI. — adults in RCTs of ginger supplementation (n = 36 trials) Evidence A source
Waist WMD -0.26 in (95% CI -0.42 to -0.09; metric: -0.65 cm, -1.07 to -0.24); body fat WMD -1.49% (-2.65 to -0.32); body weight and BMI not changed
A 2026 umbrella review of 6 meta-analyses found ginger reduced body weight by 0.95 to 3.4 lb (0.43 to 1.52 kg) across reviews, with moderate to low certainty. — 6 meta-analyses of ginger trials reporting body weight and BMI (n = 6 meta-analyses) Evidence A source
Body weight WMD range -0.95 to -3.4 lb (-0.43 to -1.52 kg); BMI WMD range -0.27 to -0.65 kg/m2; waist and body fat significant in only 1 meta-analysis each
In a 3-month double-blind RCT, 600 mg a day of ginger extract did not change energy expenditure or body composition in 66 women with excess body fat. — female participants with high body adiposity, aged 18 to 60 years (n = 66) Evidence B source
No group x time difference in resting energy expenditure, body composition or blood pressure
In the same meta-analysis, ginger did not clearly cut the number of vomiting episodes compared with placebo. — pregnant women with nausea and vomiting of pregnancy; two placebo-controlled trials pooled (n = 2 trials) Evidence A source
Vomiting episodes MD 0.72 (95% CI -0.03 to 1.46), p = 0.06, I2 71%
The Cochrane review of 41 trials with 5,449 women judged that ginger may help, but the evidence was limited and not consistent. — women up to 20 weeks' gestation with nausea, vomiting or retching; trials of hyperemesis gravidarum excluded (n = 5,449) Evidence A source
No pooled estimate for ginger; most outcomes could not be pooled
A stricter meta-analysis of 5 trials using 1.2 to 2 g of ginger powder a day for 4 to 12 weeks found no significant effect on fasting glucose or HbA1c in type 2 diabetes, so the glucose benefit depends on which trials are pooled. — Adults with type 2 diabetes in 5 randomized trials, capsules of 1.2-2 g/day for 4-12 weeks (n = 5 trials) Evidence A source
No significant pooled effect on FBS or HbA1c
Across 23 trials in chemotherapy patients, ginger did not reduce nausea overall, but up to 1 g a day for more than four days was linked to less acute vomiting (OR 0.30). — Patients receiving chemotherapy in 23 randomized trials (n = 23 trials) Evidence A source
Overall nausea and vomiting not different; acute vomiting OR 0.30 (95% CI 0.12 to 0.79) in the up-to-1 g/day subgroup

The bottom line

If you take warfarin, tell the person prescribing it before you start a ginger supplement. A review of warfarin interactions puts ginger on its watch list for bleeding, next to green tea and St. John's Wort, and a 2008 review of herb-drug interactions named ginger among the herbs most often involved, with blood thinners such as warfarin and aspirin among the drugs most often implicated. The direct tests are small and do not settle it. In 12 healthy men, a week of ginger at recommended doses did not change clotting time after a single warfarin dose. Across 8 clinical trials of platelet clumping, 4 found less and 4 found no effect. The EU medicines agency lists no known drug interactions for ginger root. In pregnancy the agencies differ. The EU medicines agency advises avoiding ginger root medicines in pregnancy as a precaution. The American health agency NCCIH says ginger supplements may be safe in pregnancy and advises checking with your provider first, and says little is known about breastfeeding. In one Danish group of 225 women in early pregnancy, 11.1 percent took ginger supplements, and most of them took it as a general health boost rather than for nausea. That is a reason to ask first, because the pregnancy evidence is about nausea only. Blood sugar is genuinely unsettled. Pooling 13 trials in type 2 diabetes, ginger lowered fasting glucose by 16 mg/dl and HbA1c by 0.41 percentage points, and the authors themselves judged that of limited clinical importance. A stricter review kept only 5 trials, all using 1.2 to 2 g of powder a day for 4 to 12 weeks, and found no effect at all. The answer depends on which trials you count, so ginger is no replacement for diabetes treatment. Because the numbers on this page run in the same direction as blood-pressure and blood-sugar medicines, a supplement on top of those drugs is a reason to ask the person who prescribes them first. Weight has the same split. An earlier review of 27 trials found about 3.3 lb (1.5 kg) lost, with low certainty, and the larger one of 36 trials found no change in weight and 0.26 in (0.65 cm) off the waist. A single 12-week trial of a steamed ginger extract at 480 mg a day lowered body fat in 80 overweight adults, but that applies to that one processed product. Across 29 trials, supplements lowered the inflammation marker CRP by 0.86 mg/L, and the studies disagreed with each other a lot, many of them in people who were already ill. In chemotherapy, 23 trials showed no overall drop in nausea or vomiting. Only a subgroup taking up to 1 g a day for more than four days vomited less in the first hours after treatment. Several things we could not find. We found no human study of ginger with diabetes medicines, and for blood-pressure medicines only one small study, in which ginger strengthened nifedipine's anti-clotting effect on platelets. No card covers kidney disease, and nothing tells you what ginger in normal cooking amounts does to anyone. Drying and heating change the compounds themselves: in lab studies dried ginger had over 9 times more 6-shogaol than fresh, so fresh root, dried powder and extracts are not interchangeable. The only nutrient row we show is for ground dried ginger.

Compared with other foods

Ginger vs turmeric — protein · calories · carbs · which is healthier

All food comparisons

Questions about ginger, answered from the trials

Ginger compared

Ginger and blood sugar: small drops, all from capsules

Related foods

Sources

hf2-gin-1 · human pharmacokinetic study
After oral dosing of 2.0 g ginger extracts in human, free 10-gingerol and 6-shogaol were detected in plasma with peak concentrations (9.5 ± 2.2 and 13.6 ± 6.9 ng/mL, respectively) at 1 h after oral administration, but no free 6-gingerol and 8-gingerol were detected in plasma from 0.25 to 24 h. The peak concentrations of glucuronide metabolites of 6-, 8-, and 10-gingerols and 6-shogaol were 0.47 ± 0.31, 0.17 ± 0.14, 0.37 ± 0.19, and 0.73 ± 0.54 μg/mL at 1 h, respectively. ... Pharmacokinetic analysis showed that half-lives of these four analytes and their metabolites were 1-3 h in human plasma. No accumulation was observed for 6-, 8-, and 10-gingerols and 6-shogaol and their metabolites in both plasma and colon tissues after multiple daily dosing.
AAPS J, 2011 · checked 2026-10-08
hf2-gin-2 · human pharmacokinetic study
Healthy subjects (n=19) were given a single dose of red ginger suspension (2 g/15 ml), and blood samples were taken at baseline (0 min), 30, 60, 90, 120, and 180 min. ... The maximum plasma concentration (Cmax) and time to reach Cmax of 10-gingerol and 6-shogaol were 160.49 ng/ml (38 min) and 453.40 ng/ml (30 min), respectively. The elimination half-lives were 336 and 149 min for 10-gingerol and 6-shogaol, respectively.
Biomed Rep, 2018 · checked 2026-10-08
hf2-gin-3 · narrative review
Shogaols are considered products derived from the dehydration of gingerols. These changes occur during long-term storage or as a result of thermal treatment, e.g., heating or drying ... On the other hand, the amount of 6-shogaol was over 9 times higher in dried ginger than in fresh ginger, both in the yellow and white varieties.
Foods, 2022 · checked 2026-10-08
hf2-gin-4 · narrative review
According to this study, 6-gingerol was relatively stable up to 37 °C, whereas at temperatures above 60 °C the degradation degree was 50%. In turn, 6-shoagol is more resistant to high temperatures and the loss of this compound at the level of 50% occurs at a temperature of 80 °C
Foods, 2022 · checked 2026-10-08
ev-gibp-01 · meta-analysis of RCTs
Ginger supplementation significantly reduced SBP (WMD: -5.03 mmHg, 95% CI: -8.49, -1.57; p = 0.004) and DBP (WMD: -2.03 mmHg, 95% CI: -3.90, -0.15; p = 0.034).
J Hum Nutr Diet, 2026 · checked 2026-10-07
ev-gibp-03 · meta-analysis of RCTs
Pooled analysis suggested that ginger supplementation can reduced systolic BP (MD: -6.36 mmHg, 95% confidence interval [-11.27, -1.46]; I2 = 89.8%; P = .011) and diastolic BP (MD: -2.12 mmHg, 95% confidence interval [-3.92, -0.31]; I2 = 73.4%; P = .002).
Phytother Res, 2019 · checked 2026-10-07
ev-gibp-05 · meta-analysis of RCTs
Ginger supplementation was not effective on the remaining outcomes.
J Diet Suppl, 2026 · checked 2026-10-07
ev-gid-02 · systematic review
All studies that observed gastric emptying rate reported ginger as a digestive enhancer, except the study from Phillips et al., where they denied the facilitation of gastric function as demonstrated by the paracetamol absorption rate [50].
Nutrients, 2020, 12(1):157 (Anh et al.) · checked 2026-10-07
ev-gid-07 · RCT
Antral area decreased more rapidly (P<0.001) and the gastric half-emptying time was less after ginger than placebo ingestion (13.1+/-1.1 vs. 26.7+/-3.1 min, P<0.01), whereas the frequency of antral contractions was greater (P<0.005).
European Journal of Gastroenterology & Hepatology, 2008, 20(5):436-440 (Wu et al.) · checked 2026-10-07
ev-gid-13 · RCT
The after-meal gastric area was significantly smaller, with a -24% difference, following the combination of extracts, as compared with placebo (p<0.001).
Eur Rev Med Pharmacol Sci, 2016 · checked 2026-10-07
ev-gimg-02 · meta-analysis of RCTs
For preventative treatment, ginger in addition to an active drug compared with the same active drug with or without placebo, may result in an important reduction in headache pain severity at 3 months (pooled MD -3.18, 95% CI -3.94 to -2.42; 2 studies, 183 participants; low certainty evidence).
BMJ Evidence-Based Medicine, 2026 (Atkins, Manger, Albarqouni) · checked 2026-10-07
ev-gimg-03 · meta-analysis of RCTs
For acute treatments, ginger with ketoprofen compared with placebo with ketoprofen may have little to no difference on headache severity at 2 hours post (mean difference (MD) 1.27 lower, 95% CI 1.46 lower to 1.08 lower; 1 study, 60 participants; low certainty evidence).
BMJ Evidence-Based Medicine, 2026 (Atkins, Manger, Albarqouni) · checked 2026-10-07
ev-gimg-04 · meta-analysis of RCTs
Overall, compared with control group in migraine patients, ginger treatment is associated with substantially improved pain free at 2 h (RR = 1.79; 95% CI = 1.04-3.09; P = 0.04) and reduced pain scores at 2 h (MD = -1.27; 95% CI = -1.46 to -1.07; P
The American Journal of Emergency Medicine, 2021 (Chen, Cai) · checked 2026-10-07
ev-gimg-05 · RCT
Results Patients treated with ginger showed significantly better clinical response after 1 h ( p = 0.04), 1.5 h ( p = 0.01) and 2 h ( p = 0.04).
Cephalalgia, 2019 (Martins et al.) · checked 2026-10-07
ev-gimg-06 · RCT
Conclusions Ginger provides no greater benefit in the prophylactic treatment of migraine when compared to placebo.
Cephalalgia, 2020 (Martins et al.) · checked 2026-10-07
ev-gimg-07 · RCT
Efficacy of ginger powder and sumatriptan was similar.
Phytotherapy Research, 2014 (Maghbooli et al.) · checked 2026-10-07
ev-gimg-08 · RCT
At 2 hours, 32% of subjects receiving active medication and 16% of subjects receiving placebo were pain-free (P= .02).
Headache, 2011 (Cady et al.) · checked 2026-10-07
ev-gimg-09 · RCT
Mixodin supplementation significantly reduced headache severity (-1.93 ± 0.30vs. -0.36 ± 0.21; P = 0.001) compared with placebo, whereas frequency and duration did not differ significantly between groups (P = 0.737 and P = 0.873, respectively).
Nutr J, 2026 · checked 2026-10-07
ev-ginf-01 · meta-analysis
CRP (WMD = -0.86 mg/L; 95% CI = - 1.10, - 0.62), TNF-α (WMD = - 1.90 pg/mL; 95% CI = - 2.61, - 1.18), IL-6 (WMD = - 1.15 pg/mL; 95% CI = - 1.90, - 0.41)
Inflammopharmacology, 2025 · checked 2026-10-07
ev-ginf-03 · meta-analysis
There was a significant reduction of circulating CRP (SMD: -5.11, 95% CI: -7.91, -2.30, I2 = 98.1%), hs-CRP (SMD: -0.88, 95% CI: -1.63, -0.12, I2 = 90.8%) and TNF-α levels (SMD: -0.85, 95% CI: -1.48, -0.21, I2 = 89.4%) following ginger supplementation.
Cytokine, 2020 · checked 2026-10-07
ev-ginf-06 · meta-analysis
Random-effects meta-regression revealed that changes in serum CRP levels were independent of the dosage of ginger supplementation (slope -0.20; 95% CI -0.95 to 0.55; p=0.60).
Food Nutr Res, 2016 · checked 2026-10-07
ev-ginf-11 · randomized controlled trial
Results: There was evidence that ginger supplementation attenuated perceptions of muscle pain in the vastus medialis; improved ratings of pain, stiffness, and functional capacity; and affected several inflammatory markers (e.g., IL-6, INF-ϒ, TNF-α, and C-Reactive Protein concentrations), particularly following two days of recovery from resistance exercise.
Nutrients, 2025 · checked 2026-10-07
ev-giwl-01 · meta-analysis of RCTs
The meta-analysis showed a significant association between ginger supplementation and a reduction in body weight (WMD, -1.52 kg; 95%CI, -2.37, -0.66; P < 0.001), BMI (WMD, -0.58 kg/m2; 95%CI, -0.87, -0.30; P < 0.001), WC (WMD, -1.04 cm; 95%CI: -1.93, -0.15; P = 0.021), and percent body fat consumption (WMD, -0.87%; 95%CI, -1.71, -0.03; P = 0.042).
Nutr Rev, 2024 · checked 2026-10-07
ev-giwl-04 · meta-analysis of RCTs
However, the small number of sample studies that investigated reductions in body weight (-0.52 (-1.48 to 0.43)) were not statistically significant.
Curr Pharm Des, 2022 · checked 2026-10-07
ev-giwl-06 · RCT
After 12 weeks of intervention, the GGE03 group showed a significant reduction in body weight compared to baseline (−1.00 ± 1.88 kg, p = 0.007), while the placebo group showed a nonsignificant increase (0.63 ± 1.92 kg, p = 0.090).
Nutrients, 2026 · checked 2026-10-07
ev-gms-01 · meta-analysis
Ginger significantly decreased nausea symptoms when compared to placebo (MD 1.20, 95% CI: 0.56 to 1.84, p = 0.0002) (Figure 3) and there was no significant heterogeneity detected between the two studies (Chi2 = 0.00, p = 1.00, I2 = 0%).
Nutrition Journal, 2014, 13:20 (Viljoen et al.) · checked 2026-10-06
ev-gms-05 · meta-analysis
Thirteen studies involving 1174 subjects were included in this meta-analysis. The result demonstrated that ginger intervention has significant effect in improving general symptom of NVP [OR = 7.475, 95% CI = (4.133, 13.520), I2 = 30.1%], relieving severity of nausea [SMD = 0.821, 95% CI = (0.585, 1.056), I2 = 38.9%], but not significant in reducing vomiting [SMD = 0.549, 95% CI = (-0.268, 1.365), I2 = 91.4%], compared with placebo.
J Matern Fetal Neonatal Med, 2022 · checked 2026-10-06
ev-gms-10 · network meta-analysis
Conclusions: This study indicates that both pharmacological (vitamin B6, metoclopramide, dimenhydrinate) and non-pharmacological (ginger, quince, acupressure, acupuncture) interventions might be effective in reducing symptoms of nausea and vomiting in pregnancy.
Nutrients, 2026 · checked 2026-10-06
ev-gms-13 · RCT
A randomized, controlled equivalence trial involving 291 women less than 16 weeks pregnant was undertaken at a teaching hospital in Australia. Women took 1.05 g of ginger or 75 mg of vitamin B6 daily for 3 weeks.
Obstet Gynecol, 2004 · checked 2026-10-06
ev-gms-14 · RCT
Ginger and vitamin B6 were more effective than placebo (p = .039 and p = .007, respectively); however, total score of Rhodes did not show significant difference between ginger and vitamin B6 (p = .128).
J Matern Fetal Neonatal Med, 2018 · checked 2026-10-06
gngb4-01 · meta-analysis of RCTs
Twelve unique RCTs contributed 13 effect sizes for SBP and 12 effect sizes for DBP. Ginger supplementation significantly reduced SBP (WMD: -5.03 mmHg, 95% CI: -8.49, -1.57; p = 0.004) and DBP (WMD: -2.03 mmHg, 95% CI: -3.90, -0.15; p = 0.034). ... GRADE assessment rated the certainty of the evidence as low, downgraded only for inconsistency.
J Hum Nutr Diet, 2026 · checked 2026-09-23
gngb4-08 · meta-analysis of RCTs
Twenty-nine RCTs were included. Our findings show that ginger supplementation improves all inflammation/anti-oxidant biomarkers, as follows: CRP (WMD = -0.86 mg/L; 95% CI = - 1.10, - 0.62)
Inflammopharmacology, 2025 · checked 2026-09-23
gngb4-09 · randomized controlled trial
Eighty adults aged 18 to 60 years, with a body mass index (BMI) of 25.0 to 29.9 kg/m2, were randomly assigned to receive either GGE03 (n = 40; 480 mg/day) or a placebo (n = 40) for 12 weeks. ... the GGE03 group showed statistically significant reductions in body fat percentage and body fat mass compared to the placebo group
Nutrients, 2026 · checked 2026-09-23
gngb4-10 · controlled clinical trial
Morning and afternoon oral intake of 1.0 g dried ginger root powder did not alter rectal temperature ... Morning ginger intake significantly reduced respiratory exchange ratios and elevated fat oxidation by 13.5 % at 120 min after ingestion. This was not the case in the afternoon.
Int J Biometeorol, 2015 · checked 2026-09-23
ev-gibp-10 · clinical study
Either aspirin or ginger could potentiate the anti-platelet aggregation effect of nifedipine in normal volunteer and hypertensive patients.
The American Journal of Chinese Medicine, 2006 (Young et al.) · checked 2026-10-07
ev-gibp-11 · prospective cohort
The CAM therapies associated with an increased risk of self-reported bleeding included cayenne, ginger, willow bark, St. John's wort, and coenzyme Q(10).
Pharmacotherapy, 2007 · checked 2026-10-07
ev-gibp-12 · systematic review
These include Chinese wolfberry, chamomile tea, cannabis, cranberry, chitosan, green tea, Ginkgo biloba, ginger, spinach, St. John's Wort, sushi and smoking tobacco.
Br J Clin Pharmacol, 2021 · checked 2026-10-07
ev-gid-04 · systematic review
Heartburn, a general symptom of gastroesophageal reflux disease, was reported in sixteen studies.
Nutrients, 2020, 12(1):157 (Anh et al.) · checked 2026-10-07
ev-gid-06 · systematic review
Ginger consumption rarely induces side effects such as mild gastrointestinal complications such as heartburn, belching, bruising or flushing, rash, and gastrointestinal discomfort.
Food Science & Nutrition, 2019, 7(1):96-108 (Nikkhah Bodagh et al.) · checked 2026-10-07
ev-gid-17 · agency monograph
Gastrointestinal disorders: Stomach upset, eructation, dyspepsia, heartburn and nausea.
European Medicines Agency, HMPC, European Union herbal monograph on Zingiber officinale Roscoe, rhizoma, Revision 1 (EMA/HMPC/885789/2022), adopted 7 May 2025 · checked 2026-10-07
ev-gid-19 · agency fact sheet
Ginger can have side effects such as abdominal discomfort, heartburn, diarrhea, and mouth and throat irritation when taken orally.
NCCIH, Ginger (fact sheet), last updated February 2025 · checked 2026-10-07
ev-gimg-10 · RCT
Clinical adverse effects of ginger powder were less than sumatriptan.
Phytotherapy Research, 2014 (Maghbooli et al.) · checked 2026-10-07
ev-gimg-11 · RCT
Feverfew/ginger was generally well tolerated with oral numbness and nausea being the most frequently occurring adverse event.
Headache, 2011 (Cady et al.) · checked 2026-10-07
ev-gimg-12 · prospective cohort
The CAM therapies associated with an increased risk of self-reported bleeding included cayenne, ginger, willow bark, St. John's wort, and coenzyme Q(10).
Pharmacotherapy, 2007 · checked 2026-10-07
ev-ginf-09 · network meta-analysis
No supplement was associated with increased adverse events compared to placebo.
Nutrients, 2025 · checked 2026-10-07
ev-giwl-08 · RCT
During the study period, adverse events were reported by eight participants (six in the GGE03 group and two in the placebo group), with no significant difference in incidence between groups (p > 0.05).
Nutrients, 2026 · checked 2026-10-07
ev-giwl-10 · agency fact sheet
Ginger can have side effects such as abdominal discomfort, heartburn, diarrhea, and mouth and throat irritation when taken orally.
NCCIH, Ginger: Usefulness and Safety (fact sheet), last updated February 2025 · checked 2026-10-07
ev-gms-03 · meta-analysis
For all reported adverse events and side-effects in the various studies [including allergic reaction [30], dehydration [30], spontaneous abortions [29,30], abdominal discomfort [29], diarrhea [29], drowsiness [19], headache [29], heartburn [19,29,30], worsening of symptoms requiring pharmaceutical treatment [30] there were no significant differences between the ginger and placebo treated groups (Table 2).
Nutrition Journal, 2014, 13:20 (Viljoen et al.) · checked 2026-10-06
ev-gms-09 · umbrella review
Taking ginger supplements (usually between 450 and 1950 mg daily) significantly decreases the severity and occurrence of nausea and vomiting compared to a placebo. This benefit is more noticeable for nausea than for vomiting, where the results are less consistent. Numerous studies have shown that ginger does not raise the risk of adverse effects, such as spontaneous abortion or side effects like heartburn and drowsiness, when compared to a placebo or vitamin B6.
Phytother Res, 2026 · checked 2026-10-06
ev-gms-11 · network meta-analysis
Patients taking ginger supplements reported loose stools (2.94%) [46], heartburn (12.1%), sedation (11.1%), and arrhythmia (1.6%) [32], as well as dizziness (3.12%) and heartburn (3.2%) [52].
Nutrients, 2026 · checked 2026-10-06
ev-gms-15 · RCT
There were some minor side effects in both groups such as sedation (26.6% vs 32.8%, p = 0.439), and heartburn (9.4% vs 6.3%, p = 0.510), a non-significant difference.
J Med Assoc Thai, 2003 · checked 2026-10-06
ev-gms-16 · prospective cohort
Among the 68,522 women in the study, 1,020 (1.5 %) women reported using ginger during pregnancy. The use of ginger during pregnancy was not associated with any increased risk of congenital malformations.
European Journal of Clinical Pharmacology, 2013, 69(2):269-277 (Heitmann, Nordeng, Holst) · checked 2026-10-06
gngb4-11 · prospective cohort
Two CAMs were independently associated with an increased risk of self-reported bleeding: coenzyme Q(10) (odds ratio [OR] 3.69, 95% confidence interval [CI] 1.88-7.24) and ginger (OR 3.20, 95% CI 2.42-4.24).
Pharmacotherapy, 2007 · checked 2026-09-23
gngb4-12 · systematic review
healthcare professionals should be aware of the increased risk of bleeding when taking several food and herbs. These include Chinese wolfberry, chamomile tea, cannabis, cranberry, chitosan, green tea, Ginkgo biloba, ginger, spinach, St. John's Wort, sushi and smoking tobacco.
Br J Clin Pharmacol, 2021 · checked 2026-09-23
hf2-gin-5 · EU herbal monograph
If the travel will continue for more than 4 hours, an additional dose may be taken every fourth hour, if needed, up to a daily dose of 2.5 g. ... Powdered herbal substance 0.25-1 g 3 times daily.
EMA/HMPC, European Union herbal monograph on Zingiber officinale Roscoe, rhizoma, EMA/HMPC/885789/2022 (revision 1) · checked 2026-10-08
hf2-gin-6 · EU herbal monograph
Interactions with other medicinal products and other forms of interaction ... None known. ... No case of overdose has been reported. ... Results from oral repeat dose toxicity studies (up to 12 months) of ethanolic ginger extracts indicate that doses which induce any potentially toxic effects are higher than what would normally be administered to humans.
EMA/HMPC, European Union herbal monograph on Zingiber officinale Roscoe, rhizoma, EMA/HMPC/885789/2022 (revision 1) · checked 2026-10-08
hf2-gin-7 · randomized crossover trial
INR and platelet aggregation were not affected by administration of ginkgo or ginger alone. ... The mean ratio (90% CI) of apparent clearance for S-warfarin was 1.05 (0.97-1.13) and for R-warfarin was 1.02 (0.95-1.10) when coadministered with ginger. The mean ratio (90% CI) of AUC(0-168) of INR was 1.01 (0.93-1.15) when coadministered with ginger.
Br J Clin Pharmacol, 2005 · checked 2026-10-08
hf2-gin-8 · systematic review
Ten studies were included, comprising eight clinical trials and two observational studies. Of the eight clinical trials, four reported that ginger reduced platelet aggregation, while the remaining four reported no effect. The two observational studies also reported mixed findings. ... The evidence that ginger affects platelet aggregation and coagulation is equivocal and further study is needed to definitively address this question.
PLoS One, 2015 · checked 2026-10-08
hf2-gin-9 · systematic review
Interestingly, herbs beginning with the letter "g" (garlic, ginger, ginkgo, and grapefruit) were among the herbs most commonly involved in herb-drug interactions. Drugs with anticoagulant/antiplatelet activity (e.g. warfarin, aspirin) were frequently implicated in herb-drug interactions, with documented interactions with over 30 herbs and herbal products.
Curr Drug Metab, 2008 · checked 2026-10-08
ev-gibp-13 · agency fact sheet
If you take any type of medicine, talk with your health care provider before using ginger or any other herbal products; some herbs and medicines interact in harmful ways.
NCCIH, Ginger (fact sheet), last updated February 2025 · checked 2026-10-07
ev-gid-16 · agency monograph
Traditional herbal medicinal product for symptomatic treatment of mild, spasmodic gastrointestinal complaints including bloating and flatulence.
European Medicines Agency, HMPC, European Union herbal monograph on Zingiber officinale Roscoe, rhizoma, Revision 1 (EMA/HMPC/885789/2022), adopted 7 May 2025 · checked 2026-10-07
ev-gimg-13 · agency fact sheet
If you take any type of medicine, talk with your health care provider before using ginger or any other herbal products; some herbs and medicines interact in harmful ways.
NCCIH, Ginger (fact sheet), last updated February 2025 · checked 2026-10-07
ev-giwl-11 · agency fact sheet
If you take any type of medicine, talk with your health care provider before using ginger or any other herbal products; some herbs and medicines interact in harmful ways.
NCCIH, Ginger: Usefulness and Safety (fact sheet), last updated February 2025 · checked 2026-10-07
ev-gms-07 · network meta-analysis
Of these interventions, ginger and vitamin B6 were also associated with better vomiting control and less incidence of adverse events. Adequate evidence supporting the use exists only for ginger and the quality of evidence for this comparison is moderate.
Expert Rev Clin Pharmacol, 2018 · checked 2026-10-06
ev-gms-12 · systematic review
There was evidence that ginger, antihistamines, metoclopramide (mild disease) and vitamin B6 (mild to severe disease) are better than placebo.
Health Technol Assess, 2016 · checked 2026-10-06
ev-gms-18 · systematic review of guidelines
There was some consensus on recommending ginger and vitamin B6 for nausea and vomiting, and additional supplementation for women with obesity.
Women Birth, 2022 · checked 2026-10-06
gngb4-04 · meta-analysis of RCTs
A total of 27 RCTs involving 1309 participants were included. The certainty in the evidence was very low for WC and BMI, and low for body weight and percent body fat as assessed by the GRADE evidence profiles. The meta-analysis showed a significant association between ginger supplementation and a reduction in body weight (WMD, -1.52 kg; 95%CI, -2.37, -0.66; P < 0.001)
Nutr Rev, 2024 · checked 2026-09-23
gngb4-05 · meta-analysis of RCTs
Thirty-six RCTs were included. Ginger supplementation significantly improved WC (WMD: -0.65 cm, 95 % CI: -1.07, -0.24) ... Ginger supplementation does not seem effective in improving major measurements/indices of weight, including body weight and BMI.
Complement Ther Med, 2025 · checked 2026-09-23
ev-gibp-02 · meta-analysis of RCTs
Subgroup-specific reductions were observed in trials enrolling participants with elevated baseline BP, using doses ≥ 2000 mg/day, including both sexes, and enrolling participants with obesity.
J Hum Nutr Diet, 2026 · checked 2026-10-07
ev-gibp-06 · meta-analysis of RCTs
Pooling data from 4 clinical trials, the model indicated that ginger significantly reduced systolic blood pressure (MD = −1.62 mmHg, 95% CI (−3.01, −0.24), I2 = 6.09%, τ2 = 0.44, and Cochran’s Q: 3.29) (Fig. 5), but not diastolic blood pressure (MD = −2.41 mmHg, 95% CI (−5.45, 0.64), I2 = 76.40%, τ2 = 6.07, and Cochran’s Q: 12.71) (Fig. 6).
Syst Rev, 2026 · checked 2026-10-07
ev-gibp-09 · RCT
No significant effects were observed on paraoxonase arylesterase activity, lipid and lipoprotein levels, body weight, or blood pressure.
Complement Ther Clin Pract, 2026 · checked 2026-10-07
ev-gid-01 · meta-analysis
Ginger-containing supplements could be meta-analyzed, and improved incidence of GERD symptom alleviation (n = 2 studies, OR: 7.50 [95%CI: 3.62-15.54], GRADE: high).
Clin Nutr ESPEN, 2022 · checked 2026-10-07
ev-gid-03 · systematic review
Lastly, one study from Miranda et al. examined the symptomatic relief on irritable bowel syndrome patients upon ginger application and found no evidence in the reduction of symptoms (p > 0.05) [54].
Nutrients, 2020, 12(1):157 (Anh et al.) · checked 2026-10-07
ev-gid-05 · systematic review
Wu et al. (2008) showed that ginger accelerates gastric emptying and stimulates antral contractions in healthy individuals; studies on patients with functional dyspepsia have shown the same results with no alterations in the fundus dimension, gastrointestinal symptoms, or serum level of gut peptides
Food Science & Nutrition, 2019, 7(1):96-108 (Nikkhah Bodagh et al.) · checked 2026-10-07
ev-gid-08 · RCT
Ginger stimulated gastric emptying and antral contractions in patients with functional dyspepsia, but had no impact on gastrointestinal symptoms or gut peptides.
World Journal of Gastroenterology, 2011, 17(1):105-110 (Hu et al.) · checked 2026-10-07
ev-gid-09 · RCT
Ginger consumption can improve constipation, nausea, bloating, and abdominal pain in patients with RRMS.
BMC Complement Med Ther, 2023 · checked 2026-10-07
ev-gid-11 · RCT
Number of treatment responders across groups was not different (57.1% placebo, 46.7% 1 gr ginger, 33.3% 2 grams ginger; p>.05).
Complementary Therapies in Medicine, 2014, 22(1):17-20 (van Tilburg et al.) · checked 2026-10-07
ev-gid-12 · RCT
The GGE03 group showed significantly improved gastrointestinal symptom rating scale (GSRS) total score and sub-scores (abdominal pain, constipation, indigestion, and reflux) compared to the placebo group
Food & Function, 2025, 16(18):7316-7329 · checked 2026-10-07
ev-gid-14 · uncontrolled before-after study
FD symptoms after ginger supplementation showed improvement in 63.7% of subjects.
Cureus, 2023, 15(9):e46061 (Aregawi et al.) · checked 2026-10-07
ev-gid-15 · uncontrolled trial
The most commonly reported adverse effects were mild bloating (14.9%), heartburn (12.8%), and diarrhea (10.6%).
Current Therapeutic Research, Clinical and Experimental, 2025, 102:100792 (Aregawi et al.) · checked 2026-10-07
ev-gid-18 · agency monograph
As a precautionary measure it is preferable to avoid the use during pregnancy.
European Medicines Agency, HMPC, European Union herbal monograph on Zingiber officinale Roscoe, rhizoma, Revision 1 (EMA/HMPC/885789/2022), adopted 7 May 2025 · checked 2026-10-07
ev-ginf-05 · meta-analysis
Pooled findings of the five RCTs demonstrated that ginger supplementations had significantly reduced hs-CRP (WMD -0.42 mg/L; 95% CI, -0.78, -0.05, P = 0.03), TNF-α (-2.13 pg/mL; 95% CI: -3.41, -0.86, P = 0.001), and IL-6 (WMD: -0.61 pg/mL; 95% CI: -0.92, -0.30, P = 0.001) levels in patients with T2DM.
Clin Nutr ESPEN, 2021 · checked 2026-10-07
ev-ginf-07 · meta-analysis
Three studies assessed the effects of ginger on OA symptoms in 166 patients compared to 164 placebo controls. Pain was the only clinical parameter that significantly decreased.
Nutrients, 2022 · checked 2026-10-07
ev-ginf-08 · network meta-analysis
and ginger (MD = 11.89, 95% CI: 1.01 to 22.49, p < 0.05) were associated with statistically significant reductions in pain.
Nutrients, 2025 · checked 2026-10-07
ev-ginf-10 · prospective cohort
The CAM therapies associated with an increased risk of self-reported bleeding included cayenne, ginger, willow bark, St. John's wort, and coenzyme Q(10).
Pharmacotherapy, 2007 · checked 2026-10-07
ev-giwl-03 · meta-analysis of RCTs
Fourteen RCTs with 473 subjects were included in our meta-analysis. The results indicated that the supplementation with ginger significantly decreased body weight (BW) (SMD -0.66; 95% CI, -1.31, -0.01; P = 0.04), waist-to-hip ratio (WHR) (SMD -0.49; 95% CI, -0.82, -0.17; P = 0.003), hip ratio (HR) (SMD -0.42; 95% CI, -0.77, -0.08; P = 0.01), fasting glucose (SMD -0.68; 95% CI, -1.23, -0.05; P = 0.03) and insulin resistance index (HOMA-IR) (SMD -1.67; 95% CI, -2.86, -0.48; P = 0.006), and significantly increased HDL-cholesterol levels (SMD 0.40; 95% CI, 0.10, 0.70; P = 0.009).
Crit Rev Food Sci Nutr, 2019 · checked 2026-10-07
ev-giwl-09 · prospective cohort
The CAM therapies associated with an increased risk of self-reported bleeding included cayenne, ginger, willow bark, St. John's wort, and coenzyme Q(10).
Pharmacotherapy, 2007 · checked 2026-10-07
ev-gms-04 · meta-analysis
Most studies provided 1000 mg of ginger powder for a period of 4 days to women suffering from NVP (with no apparent side-effects or adverse events). The literature suggests taking the total dose in three to four divided doses during the day, irrespective of mealtimes [21-23,25,26,29,30].
Nutrition Journal, 2014, 13:20 (Viljoen et al.) · checked 2026-10-06
ev-gms-06 · meta-analysis
Besides, ginger intervention has no significant effect on improving general symptom of NVP [OR = 1.239, 95% CI = (0.495, 3.102), I2 = 57.3%], relieving severity of nausea [SMD = 0.199, 95% CI = (-0.102, 0.500), I2 = 65.7%], reducing vomiting [SMD = 0.331, 95% CI = (-0.145, 0.808), I2 = 85.9%], compared with vitamin B6.
J Matern Fetal Neonatal Med, 2022 · checked 2026-10-06
ev-gms-17 · prospective cohort
Two CAMs were independently associated with an increased risk of self-reported bleeding: coenzyme Q(10) (odds ratio [OR] 3.69, 95% confidence interval [CI] 1.88-7.24) and ginger (OR 3.20, 95% CI 2.42-4.24).
Pharmacotherapy, 2007 · checked 2026-10-06
gngb4-02 · meta-analysis of RCTs
In total, 13 articles were included in this meta-analysis. Ginger supplementation was associated with a statistically significant reduction in fasting blood sugar (FBS) (MD -16.27 mg/dl, 95% CI (-25.75, -6.80), I2 = 86.39%), hemoglobin A1c (HbA1c) (MD -0.41%, 95% CI (-0.63, -0.20), I2 = 92.09%) ... however, the magnitude of these effects was of limited clinical importance.
Syst Rev, 2026 · checked 2026-09-23
gngb4-06 · meta-analysis of RCTs
Thirteen studies involving 1174 subjects were included in this meta-analysis. The result demonstrated that ginger intervention has significant effect in improving general symptom of NVP [OR = 7.475, 95% CI = (4.133, 13.520), I2 = 30.1%], relieving severity of nausea [SMD = 0.821, 95% CI = (0.585, 1.056), I2 = 38.9%], but not significant in reducing vomiting
J Matern Fetal Neonatal Med, 2022 · checked 2026-09-23
gngb4-13 · prospective cohort
Ginger supplements were consumed by 11.1%, mainly as health boost and 87.1% reported consumption of licorice.
BMC Complement Altern Med, 2019 · checked 2026-09-23
gngb4-14 · fact sheet
The use of ginger dietary supplements during pregnancy may be safe. As with all herbal supplements, if you're considering using ginger while pregnant, consult your health care provider. Little is known about whether it's safe to use ginger while breastfeeding.
NCCIH, Ginger: Usefulness and Safety, updated February 2025 · checked 2026-09-23
ev-gibp-04 · meta-analysis of RCTs
When studies were categorized based on participants' mean age, ginger dosage and duration of intervention, systolic BP and diastolic BP were significantly decreased only in the subset of studies with mean age ≤ 50 years, follow-up duration of ≤8 weeks and ginger doses ≥3 g/d.
Phytother Res, 2019 · checked 2026-10-07
ev-gibp-07 · meta-analysis of RCTs
Pooling 5 effect sizes, we found a significant reduction in SBP (WMD: -4.20; 95% CI: -7.64, -0.77, I2 =97%) and DBP [WMD: - 1.61; 95% CI: - 3.04, - 0.18), I2 = 93.2%] after supplementation with ginger.
Complement Ther Med, 2022 · checked 2026-10-07
ev-gibp-08 · RCT
No significant difference was found between various medicinal plants in terms of influencing BP, serum soluble (s)ICAM-1 concentrations and anthropometric measures.
Blood Press, 2016 · checked 2026-10-07
ev-gid-10 · RCT
Supplementation with ginger root powder was safe and altered aspects of gastrointestinal bacteria composition; however, it did not change alpha- or beta diversity, bowel function, gastrointestinal symptoms, mood, or quality of life in healthy adults.
J Nutr, 2023 · checked 2026-10-07
ev-gimg-01 · meta-analysis of RCTs
Conclusions The volume of the existing evidence is limited and combined with either a low or very low certainty of evidence, it is currently too uncertain if ginger is effective either as an acute or preventative treatment.
BMJ Evidence-Based Medicine, 2026 (Atkins, Manger, Albarqouni) · checked 2026-10-07
ev-ginf-02 · meta-analysis
Ginger supplementation may improve inflammatory and antioxidant biomarkers, particularly in individuals with underlying health conditions. Given the high heterogeneity among studies, findings should be interpreted cautiously.
Inflammopharmacology, 2025 · checked 2026-10-07
ev-ginf-04 · meta-analysis
However, meta-analysis results did not show any significant impact of ginger supplementation on IL-6 (SMD: -0.45, 95% CI: -1.29, 0.38, I2 = 89.2%), and sICAM levels (SMD: -0.05, 95% CI: -0.36, 0.26, I2 = 00.0%).
Cytokine, 2020 · checked 2026-10-07
ev-ginf-12 · meta-analysis
Pomegranate extract, Resveratrol, Garlic extract, Puerarin, Hesperidin, Ginger extract, Cinnamon extract, Sesamin only involve in 1 RCT.
Front Immunol, 2023 · checked 2026-10-07
ev-giwl-02 · meta-analysis of RCTs
Ginger supplementation does not seem effective in improving major measurements/indices of weight, including body weight and BMI.
Complement Ther Med, 2025 · checked 2026-10-07
ev-giwl-05 · umbrella review
Across 6 meta-analyses, ginger supplementation significantly reduced body weight (range of reported WMD: − 0.43 to − 1.52 kg) and BMI (range of reported WMD: − 0.27 to − 0.65 kg/m²) with moderate-to-low certainty.
Diabetology & Metabolic Syndrome, 2026, Ginger supplementation and metabolic health: an umbrella review of meta-analyses of randomized trials · checked 2026-10-07
ev-giwl-07 · RCT
Ginger extract consumption for 3 mo did not change the REE, anthropometric, and clinical data of female adults with excess adiposity.
Nutrition, 2022 · checked 2026-10-07
ev-gms-02 · meta-analysis
According to the meta-analysis, ginger failed to significantly reduce the number of vomiting episodes compared to the placebo, although it did approach significance (MD 0.72, 95% CI: -0.03 to 1.46, p = 0.06) and statistically significant heterogeneity was detected between the two studies (Chi2 = 3.44, p = 0.06, I2 = 71%).
Nutrition Journal, 2014, 13:20 (Viljoen et al.) · checked 2026-10-06
ev-gms-08 · Cochrane review
The use of ginger products may be helpful to women, but the evidence of effectiveness was limited and not consistent, though three recent studies support ginger over placebo.
Cochrane Database Syst Rev, 2015 · checked 2026-10-06
gngb4-03 · meta-analysis of RCTs
Five studies were included in the analysis. ... The dose ranged from 1.2 to 2g/day, and the intervention period ranged from 4 to 12 weeks. Meta-analysis results indicated no significant effect of ginger supplementation on FBS or HbA1c.
Clin Nutr ESPEN, 2024 · checked 2026-09-23
gngb4-07 · meta-analysis of RCTs
This study systematically reviewed 23 RCTs. ... were not significantly different between the ginger supplement intake group and the control group. However, it was found that the ginger supplement intake group, which took not more than 1 g of ginger supplementation per day for above four days, had significantly less acute vomiting than the control group (OR 0.30; 95% CI 0.12 to 0.79; p = 0.02; I2 = 36%).
Nutrients, 2022 · checked 2026-09-23

Review. Reviewed on 2026-10-08 for evidence level, dose and population context, and claims a reader could misread. Bioma Learn has no human medical reviewer at this time, and we say so rather than invent one. Methodology. This is information, not medical advice.