Does eating more protein help you build muscle?
Yes, by a small amount, and only alongside resistance training. Across 49 randomized trials in 1863 adults who trained for at least six weeks, protein supplements added 0.66 lb (0.30 kg) of fat-free mass and 5.5 lb (2.49 kg) to a one-repetition maximum. Past a total of about 1.62 g of protein per kg of body weight a day, extra protein added nothing more. Most of the gain sat in people who already lifted.
Established. Protein on top of resistance training builds slightly more lean mass than training alone. Three meta-analyses of randomized trials agree on the direction. The size is a few hundred grams over weeks to months, with 0.66 lb (0.30 kg) in the largest pooling of 49 trials.
Each bar is the difference against training without the extra protein, with its 95% confidence interval. The untrained interval crosses zero. Sources: cards ev-protmus-01, ev-protmus-03, ev-protmus-05 and prot-t10 below.
What the trials found
The main synthesis, Morton 2018, pooled 49 trials in 1863 healthy adults doing resistance training for six weeks or more. Fat-free mass rose 0.66 lb (0.30 kg) more with protein, with a confidence interval from 0.2 to 1.1 lb (0.09 to 0.52 kg). One-repetition maximum strength rose 5.5 lb (2.49 kg) more, with an interval from 1.4 to 9.5 lb (0.64 to 4.33 kg). The same analysis found a breakpoint near 1.62 g per kg a day of total protein, beyond which fat-free mass stopped climbing. The authors give that breakpoint wide uncertainty. It marks where gains level off and says nothing about safety.
The split by training history matters more than the headline. In people already used to lifting, the gain was 2.3 lb (1.05 kg), from 1.3 to 3.3 lb (0.61 to 1.50 kg). In untrained people it was 0.33 lb (0.15 kg), with an interval from minus 0.04 to 0.68 lb (0.02 to 0.31 kg) that did not reach significance. Only 10 of the trials were in trained people, and the abstract adds that the effect shrank by about 0.02 lb (0.01 kg) with each year of age.
Two other meta-analyses land in the same place. An earlier one of 22 trials in 680 younger and older people found 1.5 lb (0.69 kg) more fat-free mass and 30 lb (13.5 kg) more on the leg press. It was smaller and older, which likely explains the larger number. A pooling of 65 trials in 2907 people found lean body mass rose 1.4 lb (0.62 kg) in adults aged 18 to 121 and 1 lb (55 and 0.46 kg) in those over 55. In that review handgrip and leg press strength did not change significantly, and the timing of the protein made no difference.
Not every review agrees on muscle. In 12 trials of 261 adults aged 18 to 30, whey or soy during training did not change lean body mass, although whey improved bench press and squat performance, by mean differences of 8.87 and 9.60 in the review's own units. These were small studies. They disagree with Morton 2018 on mass and agree with it on strength.
Older adults
In older adults who lift, 21 trials in 1249 people found protein added 0.51 lb (0.23 kg) of fat-free mass and 0.86 lb (0.39 kg) of appendicular muscle, with small gains in grip and leg strength and no significant change in muscle function. An earlier review of 9 trials in 462 people with a mean age of 61 to 79 found a gain in fat-free mass, a standardized difference of 0.23, while muscle mass and strength did not change significantly. That review rated its own included studies as low quality.
In 13 trials of 1057 adults over 65 with sarcopenia or frailty, protein plus exercise raised the skeletal muscle index by 0.89 kg/m2 and grip by 5.8 lb (2.64 kg) over exercise alone. The authors rated this evidence as very low quality.
Myth. Protein alone, without exercise, has not been shown to build muscle in older adults. Across 6 randomized trials in physically inactive older people, protein supplements made no statistically significant difference to total lean body mass. The abstract does not give the total number of people.
Two recent trials that found nothing extra
In a 12-week trial of 295 frail older adults on supervised resistance training, mean age 73.9, adding whey and diet advice to reach 1.2 to 1.5 g per kg did not produce larger gains in leg press strength, appendicular lean mass or performance. In an exploratory analysis, the authors report a strength gain of 14 lb (6.4 kg) in the subgroup eating under 1.2 g per kg at the start. In a 12-week trial of 108 women aged 40 to 77 on supervised training, targets of 0.8, 1.6 or 2.2 g per kg made no detectable difference to skeletal muscle mass. Muscle there was measured by bioimpedance in 83 analyzed women, and the authors say plainly that a null result does not mean the doses are equal.
Plant or animal protein
Across 30 trials, plant protein built slightly less muscle than animal protein, a standardized difference of minus 0.20, with the gap in adults under 60. Soy matched milk protein, at minus 0.02. Rice, chia, oat and potato protein came out further behind, at minus 0.58, from only 5 trials. These are standardized differences and cannot be read as kilograms.
Mixing protein with creatine or vitamin D does not beat plain protein. Across 35 trials in 1387 people, multi-ingredient supplements added 1.8 lb (0.80 kg) of fat-free mass against all comparison groups, but that comparison pools placebo with protein-only arms, and against protein alone they showed no advantage.
Who should be careful
For healthy kidneys, the trials are reassuring over the short term. In 28 trials with 1358 adults without kidney disease, high-protein diets of at least 1.5 g per kg a day did not change kidney filtration rate over time compared with normal or lower protein. Those trials were short, and the risk of selection bias was unclear. A 2026 meta-analysis of 22 trials found high-protein diets raised eGFR without a change in serum creatinine across 19 trials in 1044 adults. The rise in eGFR may be an adaptation of blood flow, and the authors call the long-term kidney effects uncertain.
Not for everyone. People with severe kidney disease who are not on dialysis are the exception. The PROT-AGE expert group says older people with an estimated GFR below 30 may need to limit protein. If that is you, the right intake is a decision for the clinician treating your kidneys.
What expert bodies say
The International Society of Sports Nutrition says 1.4 to 2.0 g of protein per kg a day is enough for most exercising people to build and keep muscle. That is a position of a scientific society, and it sits close to the 1.62 g breakpoint in Morton 2018. A small study of 8 resistance-trained women measured after one workout put their requirement at about 1.49 to 1.53 g per kg a day, which is one session and a short recovery window. The PROT-AGE group advises people over 65 to eat at least 1.0 to 1.2 g per kg a day, and 1.2 or more if they are active.
How we searched
Searched: a local copy of the PubMed baseline on 6 October 2026, for protein, protein supplementation or whey with muscle mass, lean mass, fat-free mass, hypertrophy or resistance training. The broadest query returned 2434 records. Narrower queries covered older adults and sarcopenia, dose per kilogram and protein without exercise, plus randomized trials from 2025 and 2026. Two web searches looked for recent dose-response work and the sports nutrition position stand. Only the position stand was retrieved and used.
Included: meta-analyses of randomized trials for the main answer and for older, young, inactive and plant-protein groups, two randomized trials from 2025 and 2026, two meta-analyses and one consensus paper on kidneys, and one position stand. All PubMed identifiers were checked against Retraction Watch, with no retractions. We also reused five records already in our base: two meta-analyses in older lifters, the soy and non-soy plant protein split, a review of multi-ingredient supplements and a small study in eight trained women.
Excluded: reviews of branched-chain amino acid and amino-acid supplements, which are not whole protein. A study with only a metabolome outcome. Reviews about insects, creatine or omega-3 as the subject. A review of multimorbid older adults that found no studies on protein intake, which we record as a gap.
What we read: abstracts for most sources. Full text for Morton 2018, the 2018 kidney meta-analysis, the plant versus animal review and the position stand. The trained versus untrained split comes from the Morton full text.
What we could not get: the Tagawa dose-response meta-analyses, Nunes 2022, the Trommelen 2023 trial of a 100 g dose, the PROVIDE trial and the 2016 joint sports nutrition position, none of which are in our corpus. Full texts of the 65-trial review and of the PROT-AGE paper. A 2025 meta-regression on eating in an energy deficit, seen only in a web search.
What would change this answer
- Larger and longer randomized trials in untrained and older people at fixed targets in grams per kilogram. The current split between trained and untrained lifters rests on only 10 trials in the trained group.
- Kidney outcomes measured over years in people eating above 2 g per kg a day. The kidney trials we have are short and in people with healthy kidneys.
- Trials in older adults with several chronic diseases. A review looking for them found none that analyzed protein intake.
For protein in food, see the whey page and the protein guide.
The rest of the nutrient, in one place. Protein: who genuinely needs more of it, and what the extra does not do → What it does, how much you need, who runs short, and what too much does, with the evidence level shown on every line.
The food behind this question
- Whey: it makes you stronger without making you bigger — numbers, evidence and safety
More questions about this food
- Does protein raise blood sugar?
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- Does protein help with hair growth and hair loss?
- Does a high-protein diet cause kidney stones?
- Does a high-protein diet help during menopause?
- Does a high-protein diet help with weight loss?
- Does protein help wound healing?
- Does whey protein cause constipation?
- Does whey protein help build muscle?
- Does whey protein help older adults build muscle?
The same question for other foods (muscle growth)
Sources
- ev-protmus-01 · Meta-analysis or systematic review · systematic review and meta-analysis of RCTs · n = 1863
Data from 49 studies with 1863 participants showed that dietary protein supplementation significantly (all p<0.05) increased changes (means (95% CI)) in: strength-one-repetition-maximum (2.49 kg (0.64, 4.33)), FFM (0.30 kg (0.09, 0.52))
Who: Healthy adults in 49 RCTs of resistance training of 6 weeks or moreEffect: Fat-free mass +0.66 lb (95% CI 0.2 to 1.1; metric: 0.30 kg, 0.09 to 0.52); 1RM strength +5.5 lb (95% CI 1.4 to 9.5; metric: 2.49 kg, 0.64 to 4.33)Certainty: Main synthesis; the effect is small in kg but stable. Without training it is not included here.Br J Sports Med, 2018 · checked 2026-10-06 · we read the abstract - ev-protmus-02 · Meta-analysis or systematic review · meta-regression with two-phase breakpoint analysis · n = 1863
Protein supplementation beyond total protein intakes of 1.62 g/kg/day resulted in no further RET-induced gains in FFM.
Who: Healthy adults in RCTs of resistance trainingEffect: Breakpoint about 1.62 g/kg/day for fat-free mass gainsCertainty: The breakpoint has wide uncertainty; this is not a safety ceiling.Br J Sports Med, 2018 · checked 2026-10-06 · we read the abstract - ev-protmus-03 · Meta-analysis or systematic review · subgroup analysis within meta-analysis of RCTs · n = 1863
untrained: 0.15 kg (−0.02, 0.31), p=0.08 and trained: 1.05 kg (0.61, 1.50), p<0.0001.
Who: Untrained and resistance-trained adults in RCTs of resistance trainingEffect: Trained +2.3 lb (1.3 to 3.3; metric: 1.05 kg, 0.61 to 1.50); untrained +0.33 lb (-0.04 to 0.68; metric: 0.15 kg, -0.02 to 0.31)Certainty: Subgroup; there are only 10 trained studies. The abstract adds: the effect weakens with age (-0.01 kg per year).Br J Sports Med, 2018 · checked 2026-10-06 · we read the fulltext - ev-protmus-04 · Meta-analysis or systematic review · systematic review and meta-analysis of RCTs · n = 680
Protein supplementation showed a positive effect for FFM (weighted mean difference: 0.69 kg; 95% CI: 0.47, 0.91 kg; P < 0.00001) and 1-RM leg press strength (weighted mean difference: 13.5 kg; 95% CI: 6.4, 20.7 kg; P < 0.005) compared with a placebo after prolonged resistance-type exercise training in younger and older subjects.
Who: Younger and older subjects in 22 RCTs of resistance training over 6 weeksEffect: Fat-free mass +1.5 lb (95% CI 1 to 2; metric: 0.69 kg, 0.47 to 0.91); 1RM leg press +30 lb (95% CI 14 to 46; metric: 13.5 kg, 6.4 to 20.7)Certainty: Older and smaller synthesis; larger effect than in Morton 2018, probably because of fewer studies.Am J Clin Nutr, 2012 · checked 2026-10-06 · we read the abstract - ev-protmus-05 · Meta-analysis or systematic review · systematic review and meta-analysis of RCTs · n = 2907
The protein supplementation was effective in improving (mean difference; 95% CI) LBM in adults (0.62 kg; 0.36, 0.88) and older adults (0.46 kg; 0.23, 0.70), but not handgrip strength (older adults: 0.26 kg; -0.51, 1.04) and leg press strength (adults: 5.80 kg; -0.33, 11.93; older adults: 1.97 kg; -2.78, 6.72).
Who: Healthy adults (18 to 55 years) and older adults (over 55 years) in 65 RCTsEffect: Lean body mass +1.4 lb (0.79 to 1.9; metric: 0.62 kg, 0.36 to 0.88) adults; +1 lb (0.51 to 1.5; metric: 0.46 kg, 0.23 to 0.70) older adults; handgrip and leg press not significantCertainty: Strength did not increase significantly; timing does not matter by subgroups.J Nutr, 2020 · checked 2026-10-06 · we read the abstract - ev-protmus-06 · Meta-analysis or systematic review · systematic review and meta-analysis of RCTs · n = 1057
Combined protein and exercise interventions demonstrated significant improvements in skeletal muscle index (MD = 0.89 kg/m², 95 % CI: 0.45 to 1.33) and handgrip strength (MD: +2.64 kg, 95 % CI: +0.75 to +4.53) compared to exercise alone.
Who: Adults aged 65 or over with sarcopenia or physical frailty, 13 RCTsEffect: Skeletal muscle index +0.89 kg/m2 (0.45 to 1.33); handgrip +5.8 lb (1.7 to 10; metric: 2.64 kg, 0.75 to 4.53) versus exercise aloneCertainty: The authors rated the quality of evidence as very low.Arch Gerontol Geriatr, 2025 · checked 2026-10-06 · we read the abstract - ev-protmus-07 · Meta-analysis or systematic review · systematic review and meta-analysis of RCTs · n = —
Protein supplementation had no statistically significant effect on total lean body mass (p> 0.05).
Who: Physically inactive older adults, 6 RCTs (8 data groups)Effect: No significant effect on total lean body mass (p > 0.05)Certainty: Few studies; total N not named in the abstract.BMC Geriatr, 2025 · checked 2026-10-06 · we read the abstract - ev-protmus-08 · Meta-analysis or systematic review · systematic review and meta-analysis of RCTs · n = 261
The analysis found no significant effect of either whey or soy protein supplementation on LBM. However, protein supplement increased peak plasma total EAA with whey protein significantly improved bench press (mean difference [MD] 8.87; 95% CI: 5.95-11.79) and squat performance (MD 9.60; 95% CI: 5.61-13.60), with low to no heterogeneity.
Who: Young adults aged 18 to 30 doing resistance training, 12 RCTsEffect: Lean body mass not changed; bench press MD 8.87 (5.95 to 11.79), squat MD 9.60 (5.61 to 13.60) with whey; units not stated in the abstractCertainty: Small studies; diverges from Morton 2018 on mass, agrees on strength.J Diet Suppl, 2026 · checked 2026-10-06 · we read the abstract - ev-protmus-09 · Meta-analysis or systematic review · systematic review and meta-analysis of RCTs · n = —
Compared with animal protein, plant protein resulted in lower muscle mass following the intervention (SMD = -0.20; 95% CI: -0.37, -0.03; P = .02), with stronger effects in younger (<60 years; SMD = -0.20; 95% CI: -0.37, -0.03; P = .02) than in older (≥60 years; SMD = -0.05; 95% CI: -0.32, 0.23; P = .74) adults.
Who: Adults in 30 RCTs comparing plant with animal proteinEffect: SMD -0.20 (95% CI -0.37 to -0.03); soy versus milk SMD -0.02 (-0.20 to 0.16)Certainty: SMD, not kilograms; the difference from non-diverse plant proteins (rice, oats, potato) is larger.Nutr Rev, 2025 · checked 2026-10-06 · we read the abstract - ev-protmus-10 · Randomized controlled trial(s) · secondary analysis of a randomized controlled trial · n = 295
Overall, the protein intervention did not result in significantly greater gains in leg press muscle strength, appendicular lean mass, or physical performance compared to PRT-only (p > 0.05).
Who: 295 frail community-dwelling older adults, mean age 73.9, 69% women, 12 weeksEffect: No significant difference in leg press 1RM, appendicular lean mass or performance; protein intake +0.4 g/kg (0.3 to 0.5)Certainty: Exploratory: strength benefit in those who ate less than 1.2 g/kg at baseline (+14 lb (6.4 kg)).J Nutr Health Aging, 2026 · checked 2026-10-06 · we read the abstract - ev-protmus-11 · Randomized controlled trial(s) · randomized 2 x 3 factorial trial · n = 108
For SMM, no training-condition × protein-target interaction (p = 0.856), marginal protein-target effect (p = 0.726), or marginal training-condition effect (p = 0.273) was detected.
Who: 108 women aged 40 to 77, 12 weeks of resistance or concurrent trainingEffect: No marginal protein-target effect on skeletal muscle mass (p = 0.726)Certainty: Mass by bioimpedance; analysis of 83 people; the authors state directly that null does not mean equality of doses.J Int Soc Sports Nutr, 2026 · checked 2026-10-06 · we read the abstract - ev-protmus-12 · Meta-analysis or systematic review · systematic review and meta-analysis of RCTs · n = 1358
The change in GFR did not differ between interventions (SMD: 0.11; 95% CI: -0.05, 0.27; P = 0.16).
Who: Adults without kidney disease in 28 RCTs, more than 4 daysEffect: Change in GFR SMD 0.11 (95% CI -0.05 to 0.27), not significantCertainty: Healthy kidneys only; risk of selection bias unclear; short studies.J Nutr, 2018 · checked 2026-10-06 · we read the abstract - ev-protmus-13 · Meta-analysis or systematic review · systematic review and meta-analysis of RCTs · n = 1044
High-protein diets did not significantly change serum creatinine (19 trials; n = 1044; standardised mean difference 0.08, 95% confidence interval -0.09 to 0.25; I 2 = 20.8%), without consistent biochemical evidence suggestive of renal injury.
Who: Adults without chronic kidney disease, 22 RCTs (creatinine: 19 trials, 1044 people)Effect: eGFR SMD 0.39 (0.09 to 0.69); serum creatinine SMD 0.08 (-0.09 to 0.25); fat-free mass not significantly changedCertainty: The eGFR increase may be a hemodynamic adaptation; no long-term data.Diabetes Obes Metab, 2026 · checked 2026-10-06 · we read the abstract - ev-protmus-14 · Position of an expert body · consensus position paper · n = —
Older people with severe kidney disease (ie, estimated GFR <30 mL/min/1.73 m(2)), but who are not on dialysis, are an exception to this rule; these individuals may need to limit protein intake.
Who: Older people over 65; exception for eGFR below 30 mL/min/1.73 m2 not on dialysisEffect: At least 1.0 to 1.2 g/kg/day; 1.2 or more if active; limit with eGFR below 30Certainty: Position of the EUGMS expert group, not its own analysis.J Am Med Dir Assoc, 2013 · checked 2026-10-06 · we read the abstract - ev-protmus-15 · Position of an expert body · position stand · n = —
For building muscle mass and for maintaining muscle mass through a positive muscle protein balance, an overall daily protein intake in the range of 1.4–2.0 g protein/kg body weight/day (g/kg/d) is sufficient for most exercising individuals
Who: Exercising individualsEffect: 1.4 to 2.0 g/kg/dayCertainty: Scientific society position (T3 context), not its own meta-analysis; matches the Morton 2018 breakpoint.Jager R et al. International Society of Sports Nutrition Position Stand: protein and exercise. J Int Soc Sports Nutr, 2017 · checked 2026-10-06 · we read the fulltext - prot-t5 · Meta-analysis or systematic review · systematic review and meta-analysis of randomized trials · n = 17 and 5 trials
There was no pooled effect difference between soy and milk protein for muscle mass (SMD = -0.02; 95% CI: -0.20, 0.16; P = .80) (n = 17 RCTs), yet animal protein improved muscle mass compared with non-soy plant proteins (rice, chia, oat, and potato; SMD = -0.58; 95% CI: -1.06, -0.09; P = .02) (n = 5 RCTs)
Who: adults, 17 trials for the soy comparison and 5 for non-soy plant proteinsEffect: soy against milk protein standardized mean difference -0.02 (95% CI -0.20 to 0.16); animal against non-soy plant proteins -0.58 (-1.06 to -0.09)Certainty: small numbers of trials for the non-soy comparisonRobinson-Mitchell et al., Nutrition Reviews, 2025 · checked 2026-09-16 · we read the abstract - prot-t9 · Meta-analysis or systematic review · systematic review and meta-analysis of randomized controlled trials with resistance training of six weeks or longer · n = 1,387 participants
Data from 35 trials with 1387 participants showed significant (p<0.05) increases in FFM (0.80 kg (95% CI 0.44 to 1.15)), 1RM lower body (4.22 kg (95% CI 0.79 to 7.64)) and 1RM upper body (2.56 kg (95% CI 0.79 to 4.33)) where a supplement was compared with all non-MIP supplemented conditions (means (95% CI)).
Who: healthy adults in 35 trials; the commonest combinations were protein with creatine (17 trials) and protein with vitamin D (10 trials)Effect: against all non-multi-ingredient conditions: fat-free mass +1.8 lb (95% CI 0.97 to 2.5; metric: 0.80 kg, 0.44 to 1.15), lower-body one-rep max +9.3 lb (95% CI 1.7 to 17; metric: 4.22 kg, 0.79 to 7.64), upper-body one-rep max +5.6 lb (95% CI 1.7 to 9.5; metric: 2.56 kg, 0.79 to 4.33); no advantage over protein aloneCertainty: the comparison group pools placebo and protein-only arms, so the headline number is not a protein-versus-creatine contrastO'Bryan et al., British Journal of Sports Medicine, 2020 · checked 2026-09-17 · we read the abstract - prot-t10 · Meta-analysis or systematic review · systematic review and meta-analysis of randomized controlled trials of protein supplementation combined with resistance training · n = 1,249 participants
Twenty-one RCTs were included, involving 1,249 participants. The results showed that protein supplementation combine with RT significantly enhances the muscle mass and strength of the older adults, where FFM (fat-free mass) increased by 0.23 kg (95% CI: 0.09, 0.38; P=0.002), ASMM (appendicular skeletal muscle mass) by 0.39 kg (95% CI: 0.14, 0.64; P=0.002), handgrip strength by 0.29 kg (95% CI: 0.08, 0.50; P=0.008), knee extension strength by 0.27 kg (95% CI: 0.06, 0.47; P=0.013), leg press strength by 0.33 kg (95% CI: 0.01, 0.64; P=0.04), but no significant effects were seen on muscle function.
Who: older adults in 21 randomized trials published before May 2018Effect: fat-free mass +0.51 lb (95% CI 0.2 to 0.84; metric: 0.23 kg, 0.09 to 0.38), appendicular skeletal muscle mass +0.86 lb (95% CI 0.31 to 1.4; metric: 0.39 kg, 0.14 to 0.64), handgrip +0.64 lb (95% CI 0.18 to 1.1; metric: 0.29 kg, 0.08 to 0.50), knee extension +0.6 lb (95% CI 0.13 to 1; metric: 0.27 kg, 0.06 to 0.47), leg press +0.73 lb (95% CI 0.02 to 1.4; metric: 0.33 kg, 0.01 to 0.64); no significant effect on muscle functionCertainty: strength gains are reported in kilograms but pooled across very different tests; the split between mass and function is the point, not the exact sizeLiao et al., Journal of Nutrition, Health and Aging, 2019 · checked 2026-09-17 · we read the abstract - prot-t11 · Meta-analysis or systematic review · systematic review and meta-analysis of randomized controlled trials with resistance training of six weeks or longer · n = 462 participants
Overall, protein supplementation in combination with resistance training was associated with gains in fat-free mass, resulting in a standardized mean difference (SMD) of 0.23 [95% confidence interval (CI), 0.05-0.42]. However, protein supplementation was not associated with changes in muscle mass (0.14, 95% CI -0.05 to 0.32) or muscle strength (0.13, 95% CI -0.06 to 0.32).
Who: adults with a mean age of 61 to 79 years in 9 randomized trialsEffect: fat-free mass standardized mean difference 0.23 (95% CI 0.05 to 0.42); muscle mass 0.14 (95% CI -0.05 to 0.32) and muscle strength 0.13 (95% CI -0.06 to 0.32), both crossing no effectCertainty: the review itself rates the general quality of included studies as low, with widely varying protein doses and sourcesFinger et al., Sports Medicine, 2015 · checked 2026-09-17 · we read the abstract - prot-r2-5 · Randomized controlled trial(s) · controlled metabolic study using the indicator amino acid oxidation technique with randomized test protein intakes and biphase linear regression · n = 8 women
A mixed model biphase linear regression revealed a break point (i.e., estimated average requirement) of 1.49 ± 0.44 g·kg·d (mean ± 95% confidence interval) in Ox (r = 0.64) and 1.53 ± 0.32 g·kg·d in NB (r = 0.65), indicating a saturation in whole-body anabolism.
Who: resistance-trained women aged about 23, studied in the luteal phase after a bout of whole-body resistance exercise, over roughly eight hours of recoveryEffect: break point, that is the estimated average requirement, 1.49 g/kg/d (95% CI ±0.44) by oxidation and 1.53 g/kg/d (±0.32) by net protein balance; the safe intake at the upper confidence limit sits at the top of the 1.2 to 2.0 g/kg/d range recommended for athletesCertainty: eight participants, one session, and it measures whole-body anabolism over an eight-hour recovery window rather than long-term health or muscle gain; athlete-specific recommendations had until then rested almost entirely on studies in menMalowany et al., Medicine & Science in Sports & Exercise, 2019 · checked 2026-09-17 · we read the abstract
How this page was made. Evidence was extracted from primary sources into cards, every number was re-checked against the source, and the text was written from those cards. Bioma Learn has no human medical reviewer at this time, and we say so rather than invent one. Methodology. This is information, not medical advice.