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Is pasta bad for cholesterol?

There is no evidence that it is, and almost no evidence about pasta on its own. The main pasta meta-analysis looked for randomized trials and found no comparison that tested pasta alone. All 32 comparisons it did find, in 2,448 people, tested pasta inside low-glycemic diets, and the review measured only body weight and fat, not cholesterol. Those low-glycemic diets, where pasta is a typical staple, lowered LDL cholesterol slightly: by 6.6 mg/dL (0.17 mmol/L) in people with diabetes and by 5.8 mg/dL (0.15 mmol/L) across 25 trials in 1,973 people.

Unsettled. Whether a plate of ordinary pasta raises or lowers cholesterol has not been tested directly. A 2017 systematic review said exactly that: pasta raises blood sugar less than bread or potato, and evidence was lacking on how eating pasta affects cardiometabolic risk. Everything below is indirect, from diets that include pasta, from grain foods in general or from people who report eating it.

Fall in LDL cholesterol, mmol/L
01Low-glycemic diets, diabetes29 trial comparisons, 1,617 people0.17Low-glycemic diets, diabetes: 0.17 mmol/L (95% CI 0.08 to 0.25)Low-glycemic diets, 202625 randomized trials, 1,973 people0.15Low-glycemic diets, 2026: 0.15 mmol/L (95% CI 0.15 to 0.15)Whole grain vs refined grain24 randomized comparisons0.09Whole grain vs refined grain: 0.09 mmol/L (95% CI 0.03 to 0.15)Soy germ pasta vs ordinary pasta1 trial, 62 adults with high cholesterol0.36Soy germ pasta vs ordinary pasta: 0.36 mmol/L (95% CI 0.36 to 0.36)

The first three rows are diets and grain foods in general, with pasta at most one part of them. The last row is a pasta with soy germ added, compared with ordinary pasta, so its effect belongs to the additive. The 2026 review and the soy germ trial give no confidence interval in the abstract, so none is drawn. Sources: cards ev-pacho-03, ev-pacho-04, ev-pacho-05 and ev-pacho-07 below.

What the trials found

Low-glycemic and whole-grain diets

In a meta-analysis for the European diabetes guidelines, low-glycemic dietary patterns lowered LDL cholesterol by 6.6 mg/dL (0.17 mmol/L) against higher-glycemic diets, with a confidence interval from 0.08 to 0.25, across 29 trial comparisons in 1,617 people with diabetes. The paper graded that LDL result low certainty, and results varied a lot between trials. A 2026 meta-analysis of 25 randomized trials in 1,973 people aged 12 to 75 found LDL 5.8 mg/dL (0.15 mmol/L) lower on low-glycemic diets, with no clear change in total cholesterol, triglycerides or HDL.

Across 24 randomized comparisons, whole-grain foods lowered LDL cholesterol by 3.5 mg/dL (0.09 mmol/L) against refined-grain foods, with oats doing best. That is whole grains in general, and the review does not single out whole-wheat pasta.

Pasta itself

The trials that served pasta all changed what was in it or used it as the comparison. In 62 adults with high cholesterol, a daily 2.8 oz (80 g) serving of pasta made with soy germ lowered LDL by 14 mg/dL (0.36 mmol/L) more than ordinary pasta over 8 weeks, a fall of 8.6 percent from baseline. In a 3-month double-blind trial of 298 people with metabolic syndrome, pasta enriched with plant sterols and fiber lowered non-HDL cholesterol more than conventional pasta, and the abstract does not give the size. In both cases the added ingredient did the work.

When both groups ate whole-grain pasta, one plain and one with barley fiber and a probiotic, a serving a day for 12 weeks did not change the blood lipid profile of 41 overweight adults. Both arms ate pasta, so this trial cannot say what pasta does against no pasta.

People who eat more pasta

Among 2,562 Italian adults with type 2 diabetes, eating more pasta was not linked with LDL cholesterol or triglycerides, and was linked with lower HDL. That is one point in time, and the pasta eaters also ate less fat and protein. In about 6,000 older Spanish adults at high cardiometabolic risk, pasta intake was not linked to HDL or triglycerides, and replacing potato with pasta went with better HDL. Average pasta intake there was very low, about 9 g dry a day.

Across 17 cohorts with over 875,000 people, refined grain intake was not linked with cardiovascular disease, with a hazard ratio of 1.08 and a confidence interval from 0.99 to 1.18. The result held when the analysis kept only staple grains such as bread, pasta and white rice. The abstract gives no absolute risk, and the authors note probable unmeasured confounding.

Unsettled. Pasta has not been shown to raise LDL cholesterol. No trial has tested it directly, and among people with diabetes who eat more of it, LDL was no different. That is an absence of harm in weak data, which is not the same as proof that pasta is harmless for blood lipids.

Who should be careful

The signal that does show up is in HDL and triglycerides, the other half of the lipid panel. In a 6-week trial of 166 Chinese adults with high cholesterol, HDL fell in the group eating 3.5 oz (100 g) a day of wheat flour noodles compared with the group eating oats. The noodles were the control food, and the abstract does not give the size of the change. Among people with type 2 diabetes, those eating more pasta had lower HDL.

Not for everyone. A meta-analysis of 60 controlled feeding trials found that replacing dietary fat with carbohydrate raised fasting triglycerides. That is carbohydrate in general, not pasta, and the abstract does not give the size of the rise. If your triglycerides or HDL are already a concern, this is the finding that applies to a pasta-heavy plate.

We found no evidence on pasta and cholesterol in pregnancy, in children or with cholesterol-lowering drugs.

What expert bodies say

The American Heart Association's 2021 dietary guidance lists choosing whole grain foods and products as the third of its recommendations for a heart-healthy pattern. It says nothing about pasta specifically. We found no position on pasta and cholesterol from the AHA, the NHS or EFSA.

How we searched

Searched: a local copy of PubMed, queried on 7 October 2026 for pasta, spaghetti or noodles with cholesterol, LDL, lipids or triglycerides (93 hits, top 40 screened), and for pasta meta-analyses and systematic reviews (16 hits). Further queries covered low-glycemic diets and LDL, whole grains and LDL, refined grains and cardiovascular disease in cohorts, carbohydrate replacing fat, and observational studies of pasta. A web search for recent pasta and LDL meta-analyses found none specific to pasta. The local ClinicalTrials.gov layer had nothing for pasta and cholesterol. Every included paper was checked against Retraction Watch and none was retracted.

Included: six meta-analyses and systematic reviews of trials, four randomized trials, three observational studies and the American Heart Association's 2021 statement. Fourteen cards in all.

Excluded: reviews of functional and amaranth pastas without a lipid synthesis for pasta. A food-group network analysis with no pasta node and two whole-grain meta-analyses that overlap the one used here. An older, smaller low-glycemic review. A trial measuring only a functional cholesterol marker. Trials that replaced the whole diet or used other cereals. A press release and a glycemic index website, used only to find the originals.

What we read: abstracts for most papers, each quotation checked against the abstract text. The full text of the diabetes guideline meta-analysis, for its LDL results.

What we could not get: the full text of the 2026 low-glycemic review, so its confidence intervals are missing. The size of the non-HDL change in the plant sterol pasta trial.

What would change this answer

For what a serving of pasta holds and how it compares with other staples, see the pasta page.

The food behind this question

More questions about this food

The full guide

The same question for other foods (cholesterol)

Sources

  1. ev-pacho-01 · Meta-analysis or systematic review · systematic review and meta-analysis of randomized controlled trials (GRADE) · n = 2448
    We identified no trial comparisons of the effect of pasta alone and 32 trial comparisons (n=2448 participants) of the effect of pasta in the context of low-GI dietary patterns.
    Who: adults in randomized trials of 3 weeks or longer, pasta alone or within low-GI dietary patterns
    Effect: 0 trial comparisons of pasta alone; 32 of pasta in low-GI patterns (adiposity outcomes only, no lipid outcomes)
    Certainty: Lipids were not an outcome; the point here is the absence of pasta-alone trials.
    BMJ Open, 2018 · checked 2026-10-07 · we read the abstract
  2. ev-pacho-02 · Meta-analysis or systematic review · systematic review with meta-analysis of postprandial glucose · n = —
    Pasta meals have significantly lower postprandial glucose response than bread or potato meals, but evidence was lacking in terms of how the intake of pasta can influence cardio-metabolic disease risk.
    Who: prospective cohorts and randomized dietary trials on pasta and pasta-related fiber and grain intake
    Effect: lower postprandial glucose than bread or potato; no usable evidence on lipids or other risk factors
    Certainty: Pooled only postprandial glucose; risk-factor evidence summarized qualitatively and judged lacking.
    Nutr Metab Cardiovasc Dis, 2017 · checked 2026-10-07 · we read the abstract
  3. ev-pacho-03 · Meta-analysis or systematic review · systematic review and meta-analysis of randomized controlled trials (GRADE), for EASD guidelines · n = 1617
    Low GI/GL diets showed moderate reductions in non-HDL-C (mean difference −0.20 mmol/L (95% confidence interval −0.33 to −0.07), P=0.002; substantial heterogeneity, I2=70%, P<0.001); small important reductions in LDL-C (−0.17 mmol/L (−0.25 to −0.08), P<0.001; substantial heterogeneity, I2=70%, P<0.001), ...
    Who: 1617 people with type 1 or type 2 diabetes, mostly middle aged and overweight, in trials of 3 weeks or longer
    Effect: LDL-C MD -6.6 mg/dL (95% CI -9.7 to -3.1; metric: -0.17 mmol/L, -0.25 to -0.08), I2 70%; non-HDL-C -7.7 mg/dL (-0.20 mmol/L); triglycerides -8 mg/dL (-0.09 mmol/L)
    Certainty: Dietary patterns, not pasta alone; LDL-C graded low certainty in the paper.
    BMJ, 2021 · checked 2026-10-07 · we read the fulltext
  4. ev-pacho-04 · Meta-analysis or systematic review · systematic review and meta-analysis of randomized controlled trials · n = 1973
    Low-GI diets significantly reduced fasting blood glucose (FBG; -0.19 mmol/L, p = 0.04), glycated hemoglobin (HbA1c; -0.22%, p < 0.01), and low-density lipoprotein cholesterol (LDL-C; -0.15 mmol/L, p < 0.01) compared with control diets.
    Who: participants aged 12 to 75 in randomized trials of low-GI vs control diets, searched to April 2025
    Effect: LDL-C -5.8 mg/dL (-0.15 mmol/L) (p < 0.01); total cholesterol, triglycerides and HDL-C not significantly changed
    Certainty: Diet patterns, not pasta; confidence interval not in the abstract.
    Curr Diabetes Rev, 2026 · checked 2026-10-07 · we read the abstract
  5. ev-pacho-05 · Meta-analysis or systematic review · systematic review and meta-analysis of randomized controlled trials · n = 24 studies
    Overall, whole-grain intake lowered LDL cholesterol (weighted difference: -0.09 mmol/L; 95% CI: -0.15, -0.03 mmol/L; P < 0.01) and TC (weighted difference: -0.12 mmol/L; 95% CI: -0.19, -0.05 mmol/L; P < 0.001) compared with the control.
    Who: adults in randomized controlled comparisons of whole-grain vs non-whole-grain foods
    Effect: LDL-C -3.5 mg/dL (95% CI -5.8 to -1.2; metric: -0.09 mmol/L, -0.15 to -0.03); total cholesterol -4.6 mg/dL (95% CI -7.3 to -1.9; metric: -0.12 mmol/L, -0.19 to -0.05)
    Certainty: Whole grains in general, not whole-wheat pasta specifically.
    Am J Clin Nutr, 2015 · checked 2026-10-07 · we read the abstract
  6. ev-pacho-06 · Meta-analysis or systematic review · meta-analysis of controlled feeding trials · n = 60 trials
    Replacing fats with carbohydrates increased fasting triacylglycerol concentrations.
    Who: participants in 60 controlled feeding trials of dietary fat and carbohydrate
    Effect: fasting triacylglycerol higher when carbohydrate replaced fat; total:HDL ratio unchanged when carbohydrate replaced saturated fat
    Certainty: Carbohydrate in general, not pasta; size of the triglyceride rise not in the abstract.
    Am J Clin Nutr, 2003 · checked 2026-10-07 · we read the abstract
  7. ev-pacho-07 · Randomized controlled trial(s) · randomized controlled parallel trial · n = 62
    Soy germ pasta reduced serum total and LDL cholesterol by 0.47 +/- 0.13 mmol/L (P = 0.001) and 0.36 +/- 0.10 mmol/L (P = 0.002) more than conventional pasta, representing reductions from baseline of 7.3% (P = 0.001) and 8.6% (P = 0.002), respectively.
    Who: adults with hypercholesterolemia on a Step II diet with one 2.8 oz (80 g) serving of pasta a day, 8 weeks
    Effect: total cholesterol -18 mg/dL (-0.47 mmol/L) and LDL-C -14 mg/dL (-0.36 mmol/L) vs conventional pasta (-7.3% and -8.6% from baseline)
    Certainty: Effect comes from the soy isoflavones added, not pasta; ordinary pasta was the control.
    J Nutr, 2007 · checked 2026-10-07 · we read the abstract
  8. ev-pacho-08 · Randomized controlled trial(s) · randomized double-blind controlled trial · n = 298
    The participants who consumed the experimental pasta exhibited a significantly greater reduction in serum non-HDL-C levels compared to the control group (p = 0.001).
    Who: adults with metabolic syndrome, with and without major psychiatric disorders, experimental or conventional pasta for 3 months
    Effect: greater reduction in non-HDL-C vs conventional pasta (p = 0.001); size not in the abstract
    Certainty: Effect of the added phytosterols, arabinoxylans and unsaturated fats; mmol/L change not in the abstract.
    Eur Psychiatry, 2025 · checked 2026-10-07 · we read the abstract
  9. ev-pacho-09 · Randomized controlled trial(s) · single-blind parallel randomized placebo-controlled trial · n = 41
    RESULTS: INN or CTR pasta consumption had no effect on primary and secondary outcomes over time, except for a significant increase in plasma γ-glutamyltransferase (GGT) after 12 wk of CTR pasta consumption.
    Who: healthy sedentary overweight or obese adults aged 30 to 65, one serving a day of whole-grain control or synbiotic pasta, 12 weeks
    Effect: no effect on fasting lipid profile over time in the whole group; LDL/HDL ratio lower only in an obese subgroup on synbiotic pasta
    Certainty: Both arms ate pasta; no non-pasta control.
    J Nutr, 2019 · checked 2026-10-07 · we read the abstract
  10. ev-pacho-10 · Randomized controlled trial(s) · randomized controlled parallel-arm trial · n = 166
    HDL-cholesterol decreased significantly in the control group versus the oat group.
    Who: adults with mild to moderate hypercholesterolemia in Beijing, 100 g/day instant oats (n = 85) or wheat flour noodles (n = 81), 6 weeks
    Effect: HDL-C decreased in the noodle group vs the oat group; total and LDL-C fell with oats vs noodles
    Certainty: Noodles were the control food; size of the HDL change not in the abstract.
    Nutr J, 2012 · checked 2026-10-07 · we read the abstract
  11. ev-pacho-11 · Observational data · cross-sectional analysis · n = 2562
    No relation was found with LDL cholesterol and triglycerides, but there was an inverse relation with HDL-cholesterol.
    Who: adults with type 2 diabetes in Italy, EPIC food questionnaire, sex-specific quartiles of pasta intake
    Effect: no relation with LDL-C or triglycerides; inverse relation with HDL-C
    Certainty: Association at one time point; pasta eaters also ate less fat and protein.
    Nutrients, 2019 · checked 2026-10-07 · we read the abstract
  12. ev-pacho-12 · Observational data · longitudinal analysis within a randomized trial cohort · n = about 6000
    Replacing potato with pasta was associated with improvements in diastolic BP and HDL-cholesterol.
    Who: older PREDIMED-Plus participants with overweight or obesity at high cardiometabolic risk, food questionnaires over 2 years
    Effect: no association of pasta with HDL-C or triglycerides at 1 year; substituting pasta for potato associated with improved HDL-C
    Certainty: Observational; very low mean pasta intake (about 9 g dry a day).
    J Am Nutr Assoc, 2025 · checked 2026-10-07 · we read the abstract
  13. ev-pacho-13 · Observational data · meta-analysis of prospective cohort studies · n = over 875,000
    The lack of association between refined grain intake and CVD risk was observed in meta-analyses of studies that restricted analyses to only staple grain foods (e.g., bread, cereal, pasta, white rice), as well as for meta-analyses of studies that included both staple and indulgent grain foods (e.g., cakes, cookies, doughnuts, brownies, muffins, pastries).
    Who: adults in 17 prospective cohort studies
    Effect: CVD HR 1.08 (95% CI 0.99 to 1.18), I2 70%; same null result when limited to staple grain foods
    Certainty: Observational; probable unmeasured confounding noted by the authors.
    Trends Cardiovasc Med, 2024 · checked 2026-10-07 · we read the abstract
  14. ev-pacho-14 · Position of an expert body · scientific statement · n = —
    Evidence-based dietary pattern guidance to promote cardiometabolic health includes the following: ... (3) choose whole grain foods and products; ...
    Who: general population, cardiometabolic health
    Effect: recommendation 3 of 10: choose whole grain foods and products
    Certainty: Pattern-level advice; no statement on pasta specifically.
    American Heart Association, Circulation, 2021, Dietary Guidance to Improve Cardiovascular Health: A Scientific Statement From the American Heart Association · checked 2026-10-07 · we read the abstract

How this page was made. Evidence was extracted from primary sources into cards, every number was re-checked against the source, and the text was written from those cards. Bioma Learn has no human medical reviewer at this time, and we say so rather than invent one. Methodology. This is information, not medical advice.

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