Mixed vegetable juice: the drink the juice reviews left out

In an individual participant meta-analysis of 4 randomized trials in 85 adults aged 55 to 76, the pooled effect of high-nitrate beetroot juice on blood pressure did not reach significance. Only in those under 65 did it lower night-time systolic pressure variability, by 2.8 mmHg, in a small sample split into subgroups. That is beetroot juice, and mixed vegetable juice is a different drink. An umbrella review of 15 systematic reviews on 100 percent juice found no eligible meta-analysis on vegetable juice at all. What a glass holds is clearer. One cup, 246 g, gives about 69 calories, 684 mg of potassium, 202 mg of sodium and 1,203 micrograms RAE of vitamin A from carotenoids. Those numbers come from a single USDA survey record, recalculated from 100 g, and sodium can differ a lot between regular and low-sodium brands.

As people eat it, per 3.5 oz (100 g)

How much is actually in it

• Per 100 g, mixed vegetable juice in the USDA survey database carries 28 calories, 2.62 g of sugars, 278 mg of potassium, 82 mg of sodium and 489 micrograms RAE of vitamin A. — USDA FNDDS food code 75132000, mixed vegetable juice; single survey record, no sample spread (n = 1 record) Evidence E source
  Energy 28 calories, sugars 2.62 g, potassium 278 mg, sodium 82 mg, vitamin A 489 ug RAE, vitamin C 5.8 mg per 3.5 oz (100 g)

What a real portion looks like

• One cup of mixed vegetable juice (246 g) gives about 69 calories, 684 mg of potassium, 202 mg of sodium and 1,203 micrograms RAE of vitamin A. — USDA FNDDS portion weights for mixed vegetable juice, food code 75132000 (n = 3 portion measures) Evidence E source
  1 cup 246 g: 68.9 calories, 683.9 mg potassium, 201.7 mg sodium, 1202.9 ug RAE vitamin A, 6.4 g sugars

What your body absorbs

• In 21 young women, 7.1 oz (200 g) of tomato juice with lemon juice and perilla oil drunk 10 minutes before white rice kept 30-minute glucose at 103.1 mg/dL versus 127.8 mg/dL after water. — 21 women (age 21.1±0.6 y), 200 g tomato juice, tomato juice with 10 g lemon juice and 5 g perilla oil, or water before 200 g boiled white rice (n = 21) Evidence B source
  30-min plasma glucose 103.1 vs 127.8 mg/dL with water (p<0.001); plain tomato juice 113.9 mg/dL, a trend versus the enriched juice (p=0.078)

What it does to your health

• Cross-sectional data from Serbia link drinking pure fruit or vegetable juice less than once a week with about 3 times higher odds of elevated blood pressure in 19-year-olds. — 212 participants aged 19 from the 2019 Fourth National Health Survey of Serbia (n = 212) Evidence C source
  OR 3.239 (95% CI 1.413 to 7.427) for elevated blood pressure with juice less than once per week

Safety, limits and interactions

• FDA warns that untreated, unpasteurised juice can cause serious illness or death in children, older adults, pregnant women and people with weakened immunity. — consumers in the United States, with higher risk in children, older adults, pregnant women and immunocompromised people Evidence E source
  Risk of serious illness or death from untreated juice in vulnerable groups; most juice sold in the United States is pasteurized
• A 68-year-old man who drank a spinach-heavy juice daily for six months, about 1,500 mg of oxalate a day, developed acute oxalate nephropathy and remained on dialysis a year later. — a 68-year-old man with adequate baseline renal function on a daily oxalate-rich fruit and vegetable juice diet (n = 1) Evidence D source
  About 1500 mg oxalate a day, about 10 times a typical diet; end-stage renal disease, dialysis dependent at one year
• Among 65 Mayo Clinic patients with biopsy-confirmed kidney oxalate crystals, three had presumed diet-induced oxalate nephropathy on top of chronic kidney disease, one of them from heavy juicing. — 65 patients seen at Mayo Clinic from 1985 through 2010 with renal failure and biopsy-confirmed renal calcium oxalate crystals (n = 65) Evidence C source
  3 of 65 with presumed diet-induced oxalate nephropathy in chronic kidney disease

What people believe that the data does not support

• The European Union refused the claim that tomato juice has a positive influence on blood sugar. — European Union food labeling, claim on tomato juice Evidence E source
  Claim non-authorized
• The European Union also refused the claim that antioxidants in processed fruit and vegetable juices protect the body, so juice cannot be sold in Europe as an antioxidant shield. — European Union food labeling, claim on antioxidants from processed fruits, vegetables and juices Evidence E source
  Claim non-authorized; no authorized claim for vegetable juice in the snapshot

Who this works differently for

• In an individual participant meta-analysis of 4 randomized trials in 85 adults aged 55 to 76, beetroot juice lowered nocturnal systolic pressure variability by 2.8 mmHg only in those under 65. — 85 older participants (age range: 55-76 years) from four randomized clinical trials of high-nitrate beetroot juice versus placebo (n = 85) Evidence A source
  Pooled effect on all BP outcomes not significant; under 65: -2.8 mmHg nocturnal systolic variability (p = 0.002); 65 and over: 1.0 mmHg (p = 0.54)

What is still unknown

• An umbrella review of 15 systematic reviews on 100% juice found no eligible meta-analysis on vegetable juice at all, and most fruit juice analyses showed no effect. — 15 systematic literature reviews with 51 primary meta-analyses of 100% juice at 50-1200 mL/day (n = 15 reviews, 51 meta-analyses) Evidence C source
  10 of 51 meta-analyses (19.6%) reported benefits, 3 (5.9%) adverse risks, 74.5% no effect; zero on vegetable juice

The bottom line

In 21 young women, 7.1 oz (200 g) of tomato juice with lemon juice and perilla oil, drunk 10 minutes before white rice, kept 30-minute glucose at 103.1 mg/dL against 127.8 mg/dL after water, at a single meal. Plain tomato juice landed at 113.9 mg/dL, only a trend against the enriched juice (p = 0.078). Cross-sectional data from Serbia link drinking pure fruit or vegetable juice less than once a week with about 3 times higher odds of elevated blood pressure in 19-year-olds (OR 3.24, 95% CI 1.41 to 7.43, 212 people). That is one small snapshot with fruit and vegetable juice counted together, so it cannot say which came first. The European Union refused two claims a juice label might make. One said tomato juice has a positive influence on blood sugar, and the other said antioxidants in processed fruit and vegetable juices protect the body. Refusal means the evidence fell short when it was assessed, and our snapshot holds no authorized claim for vegetable juice. The cautions in our sources concern raw and homemade juice. FDA warns that untreated, unpasteurised juice can cause serious illness or death in children, older adults, pregnant women and people with weakened immunity, without giving a number for the risk, and most juice sold in the United States is pasteurized. A 68-year-old man who drank a homemade spinach-heavy juice every day for six months, about 1,500 mg of oxalate a day, developed acute oxalate nephropathy and was still on dialysis a year later. That is a single case, with dehydration also involved. In a Mayo Clinic series of 65 patients with oxalate crystals in the kidney, 3 had presumed diet-induced oxalate nephropathy on top of chronic kidney disease, one of them from heavy juicing. If you have kidney disease, a daily habit of oxalate-rich homemade juice is a question for the person treating you.

Sources

1. mvj-r8-01 · food composition data
   Mixed vegetable juice, FNDDS 75132000, fdc_id 2709810, per 100 g: Energy 28 KCAL · Total Sugars 2.62 G · Potassium, K 278 MG · Sodium, Na 82 MG · Vitamin A, RAE 489 UG · Vitamin C, total ascorbic acid 5.8 MG
   USDA FNDDS, food code 75132000, FDC 2709810 · checked 2026-10-02
2. mvj-r8-02 · portion data
   Mixed vegetable juice, fdc_id 2709810: 1 cup 246 g · Energy 68.9 KCAL · Potassium 683.9 MG · Sodium 201.7 MG · Vitamin A, RAE 1202.9 UG · Total Sugars 6.4 G; Quantity not specified 123 g; 1 fl oz 31 g
   USDA FNDDS, food code 75132000, FDC 2709810 · checked 2026-10-02
3. mvj-r8-07 · randomized crossover trial
   The plasma glucose at 30 min in tomato juice with lemon/n-3 PUFA-rich oil was significantly lower than that of water (103.1±3.4 mg/dL vs. 127.8±4.0 mg/dL, p<0.001, mean±SE) and tended to be lower than that of tomato juice (113.9±4.9 mg/dL, p=0.078).
   J Nutr Sci Vitaminol (Tokyo), 2025 · checked 2026-10-02
4. mvj-r8-11 · cross-sectional
   In multivariate logistic regression, elevated arterial blood pressure was significantly associated with consuming pure fruit or vegetable juices less than once per week (OR = 3.239; 95% CI: 1.413-7.427)
   Medicina (Kaunas), 2026 · checked 2026-10-02
5. mvj-r8-03 · regulatory guidance
   While most people's immune systems can usually fight off the effects of foodborne illness, children, older adults, pregnant women, and people with weakened immune systems (such as transplant patients and individuals with HIV/AIDS, cancer, or diabetes) risk serious illnesses or even death from drinking untreated juices.
   US Food and Drug Administration, What You Need to Know about Juice Safety · checked 2026-10-02
6. mvj-r8-04 · case report
   We describe a 68-year-old man with adequate baseline renal function who developed severe AON and ESRD. Six months earlier, he started a daily oxalate-rich fruit and vegetable juice diet high in spinach, with a calculated daily oxalate dietary intake of 1500 mg, about 10 times a typical diet...A year later, he remains dialysis dependent.
   Case Rep Nephrol, 2022 · checked 2026-10-02
7. mvj-r8-05 · case report and case series
   Three patients, including our index patient, had presumed diet-induced oxalate nephropathy in the context of chronic kidney disease...Clinicians should be aware that an oxalate-rich diet may potentially precipitate acute renal failure in patients with chronic kidney disease.
   Am J Med, 2013 · checked 2026-10-02
8. mvj-r8-09 · regulatory register entry
   POL-HC-8038 Tomato juice Tomato juice has a positive Influence on blood sugar level Non-authorised
   EU Register on nutrition and health claims, claim POL-HC-8038, snapshot 2026-09-21 · checked 2026-10-02
9. mvj-r8-10 · regulatory register entry
   POL-HC-6611 Antioxidant from processed fruits and vegetables and juices Antioxidant contained in this product contribute to the anti-oxidative functions of the body/ensure protective effect on the organism Non-authorised
   EU Register on nutrition and health claims, claim POL-HC-6611, snapshot 2026-09-21 · checked 2026-10-02
10. mvj-r8-06 · IPD meta-analysis of RCTs
    Eighty-five older participants (age range: 55-76 years) were included in the final database...The pooled effect of beetroot juice on all BP outcomes was not significant. Beetroot juice ingestion determined a significant decrease in nocturnal systolic BP variability in subjects aged less than 65 y (2.8 mmHg, -4.5 -1.0, p = 0.002) compared to the older group (≥ 65 y; 1.0 mmHg, -2.2 4.2, p = 0.54).
    Nitric Oxide, 2015 · checked 2026-10-02
11. mvj-r8-08 · umbrella review
    No eligible studies for vegetable juice were found. Fifteen systematic literature reviews (51 primary MAs, 6 dose-response, and 87 subanalyses; 50-1200 mL/day; hours to years of duration) were included.
    Nutr Rev, 2025 · checked 2026-10-02